Macrolides Flashcards

1
Q

Macrolides Example

A

Erythromycin (E-Mycin), the prototypical macrolide, has been used in treating many infections over the years. However, its use has been diminished by GI side effects.

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2
Q

Macrolides Distribution

A

oral; are absorbed from the GI tract; have good tissue penetration, high intracellular concentration, and minimal protein binding

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3
Q

Macrolides Elimination

A

Metabolized by the liver

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4
Q

Macrolides Clinical uses

A

treating respiratory tract, skin, and soft-tissue infections; sexually transmitted diseases; HIV-related Mycobacterium avium–intracellulare complex infection; and other infections caused by atypical organisms.

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