Cardiomyopathies Flashcards

1
Q

dyspnea

A

shortness of breath

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2
Q

tachypnea

A

increased respiratory rate

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3
Q

syncope

A

fainting

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4
Q

tachycardia

A

increased heart rate

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5
Q

cardiomyopathy

A
  • disorder within the cardiac myocytes themselves which results in abnormal cellular and cardiac performance
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6
Q

what happens to EF when you have cardiomyopathy

A

reduces - predicts mortality and morbidity

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7
Q

dilated cardiomyopathy

A
  • chamber dilation and contractile impairment resulting in decreased EF & SV
  • ballooning of the LV
  • leads to heart failure
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8
Q

what does cardiac remodeling lead to in dilated cardiomyopathy

A
  • heavier than normal heart
  • hypertrophied cardiac myocytes
  • loss of myofibrils, reduced mitochondrial function
  • fibrosis occurs
  • chamber walls thin
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9
Q

causes of dilated cardiomyopathy

A
  • genetic mutations
  • viral infections like HIV
  • various toxins
  • metabolic disorders
  • myocarditis
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10
Q

symptoms of dilated cardiomyopathy

A
  • fatigue
  • dyspnea on exertion
  • SOB
  • cough
  • orthopnea
  • paroxysmal nocturnal dyspnea
  • edema
  • weight gain
  • abdominal girth
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10
Q

signs of dilated cardiomyopathy

A
  • tachypnea
  • tachycardia
  • HTN or hypotension
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11
Q

what happens to LV EDV in dilated cardiomyopathy

A
  • the overstretching increases it, leads to failure of the myocardial contractile unit
  • frank starling compromised
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12
Q

hypertrophic cardiomyopathy

A
  • common cause of death in healthy young people
  • thicken LV wall with a non-dilated LV chamber –> EDV limited
  • dont have HTN but have chronic afterload on the heart
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13
Q

gene defects of hypertrophic cardiomyopathy

A

heart lays down more sarcomeres than needs = compromises movement of sarcomeres

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14
Q

obstructive HCM

A

septal wall thickens and the LV free wall of the ventricles stiffen

obstructing blood flow into the aorta

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15
Q

nonobstructive HCM

A

walls of the LV stiffen, reduces LV EDV and SV

blood flow not blocked

16
Q

signs and symptoms of HCM

A
  • chest pain
  • SOB
  • fatigue
  • arrhythmias
  • dizzy
  • lightheadedness
  • fainting
  • swelling in ankles, feet, legs, abdomen, veins in neck
17
Q

HCM long term complications

A
  • atrial fibrillation
  • dyrhythmia
  • heart failure
  • history of MI
18
Q

treatment HCM

A
  • alcohol septal ablation
  • implantable cardioverter defibrillator
  • heart transplant
19
Q

restrictive/infiltrative cardiomyopathy

A
  • restricted diastolic filling/loss of compliance; diastolic dysfunction
  • rigid heart walls
  • systolic normal
  • EDV diminished
20
Q

in people with restrictive/infiltrative cardiomyopathy, their ESVs and EFs are what..

A

normal

21
Q

in people with restrictive/infiltrative cardiomyopathy, their SV is what..

A
  • compromised

- ventricular filling is high

22
Q

symptoms of restrictive/infiltrative cardiomyopathy

A

dyspnea with exertion
abdominal swelling
ankle edema
fatigue

23
Q

causes of restrictive/infiltrative cardiomyopathy

A
scleroderma
amyloidosis
sarcoidosis
diabetes
hemochromatosis
chemo agents 
radiation