Inflammation Flashcards
inflammation
organized vascular and cellular response of the body from cell injury and death
erythema
redness
vasodilation and increased blood flow
exudate
allows for the passage of a protein and cell rich fluid into the interstitial spaces
neutrophils
first responder for acute inflammation
attract WBC and tell where to go
monocytes
circulate in blood
go to injury side after neutrophils and mature into macrophages
macrophages
a WBC that engulfs and digest cellular debris, foreign substances, microbes, cancer cells
lymphocytes
WBC, lymph
produce antibodies
mast cells
found in most tissues
large granules which hold several performed immune mediators
diapedesis
when the cell lining separates to allows things through
chemotaxis
type of cytokines
small proteins secreted by cells that influence the immune system, they attract cells to an area of injury that bring about changes to the endothelial lining for cells to go out of vasculature to the site of injury and squeeze between the lining
cytokines
signaling molecules that regulate inflammation and immune response in health and disease
act on cells with autocrine, paracrine, and endocrine
leukocytosis
increased WBC
what is normal WBC count
4000-10000 cells/ul
leukopenia
decreased WBC count
viral infection, protozoan, rickettsial and some bacterial infections
what cardinal sign will you see with leukopenia
fever
