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mls 3H > CC Lec M7 > Flashcards

CC Lec M7 Flashcards

1
Q

Parent drug of Digitoxin

A

Digoxin

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2
Q

Inhibits NA-K ATPase

A

Digoxin

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3
Q

Quinidine trough level

A

1 hour after last dose

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4
Q

Tacrolimus trough level

A

5 minutes before next dose

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5
Q

Metabolism of quinidine

A

n-acetylation

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6
Q

Metabolite of quinidine

A

N-acetylprocainamide

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7
Q

Parent drug of procainamide

A

Quinidine

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8
Q

What has anticholinergic and cardiac effects

A

Disopyramide

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9
Q

Undergoes Dealkylation

A

Lidocaine

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10
Q

For gram-negative

A

Aminoglycosides

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11
Q

For gram-positive

A

Vancomycin

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12
Q

Ototoxicity, Nephrotoxicity, and Red Man syndrome

A

Vancomycin

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13
Q

Drug method: chromogenic and immunoassays

A

Vancomycin and Aminoglycosides

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14
Q

Metabolite: Primidone; Parent drug:

A

Phenobarbital

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15
Q

Liquid form of Phenytoin:

A

Fosphenytoin

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16
Q

Other name: Dilatin

A

Phenytoin

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17
Q

Other name: Depakene

A

Valproic Acid

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18
Q

Enhances GAB

A

Valproic Acid

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19
Q

Inhibits Lamotrigine

A

Valproic Acid

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20
Q

Decreases motor complex

A

Ethosuximide

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21
Q

Reduced half-life when administered with:
1. Phenobarbital
2. Phenytoin
3. Primidone
4. Carbamazepine

A

Felbamate

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22
Q

Elimination is higher in children and pregnant women

A

Levetiracetam

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23
Q
  1. For complex partial seizure
  2. Treats acute intermittent porphyria
  3. Parent drug that can’t be broken down
A

Gabapentin

24
Q
  1. Tonic clonic seizure
  2. Pro-drug
A

Oxcarbazepine

25
Q

Metabolite: Licarbazepine

A

Oxcarbazepine

26
Q
  1. Partial seizure
  2. Experiences the ff: confusion, stuttering, mild sedation, and paresthesia
A

Tiagabine

27
Q

Pins & needles
Change of taste

A

Topiramite

28
Q

Other name: Tegritol

A

Carbamazepine

29
Q

Manic depression

A

Lithium

30
Q

Methods: ISE, FEP, or AAS

A

Lithium

31
Q

Inhibits Thyroid Secretion

A

Lithium

32
Q

Inhibits: catecholamines

A

Tricyclic Anti-depressant

33
Q

Competes with Sodium and Potassium

A

Monovalent

34
Q

Competes with Calcium and Magnesium

A

Divalent

35
Q
  1. Treats: Depression, insomia, extreme apathy, loss of libido
  2. Blocks catecholamines
A

Tricyclic anti-depressant

36
Q

Inclined with Parkinsonian syndrome

A

Tricyclic antidepressant

37
Q

Suicidal attempt/tendecies

A

Clozapine

38
Q

Recurrence bipolar, acute manic episodes

A

Olanzapine

39
Q

Treats OCDs

A

Fluoxetine

40
Q

Blocks serotonin

A

Fluoxetine

41
Q
  1. Suppresses host vs graft
  2. Blocks IL-2
A

Cylcosporine

42
Q

Marked affinity with RBC

A

Cylcosporine

43
Q
  1. Same action with cyclosporine but 100x stronger
  2. Choliestasis
A

Tacrolimus (FK-506)

44
Q

Method: High performance liquid chromatography-mass spectrophotometry

A

Tacrolimus

45
Q
  1. Antifungal
A

Sirolimus

46
Q

Other name: Rapamycin

A

Sirolimus

47
Q

Specimen of choice:whole blood

A

Sirolimus

48
Q

Blocks: Lymphocyte

A

Mycophenolic acid

49
Q

Metabolite of Mycophenolic acid

A

Mycophenolate acid mofetil

50
Q

Parent drug of Mycophenolic acid

A

Mycophenolate mofetil

51
Q

Blocks: Dihydrofolate reductase (enzyme) w/c inhibits DNA

A

Methotrexate

52
Q

Reverses methotrexate:

A

Leucovorin

53
Q

Treats leukemia and lymphoma in neonates

A

Busulfan

54
Q

Treatment for asthma that blocks Phophodiesterase

A

Theophylline

55
Q

Other name: Tylenol

A

Acetaminophen

56
Q

Inhibits: prostaglandin cylcooxygenase

A

Acetaminophen

57
Q

Inhibits: prostaglandin synthase

A

Aspirin

mls 3H (12 decks)

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