CC Lec M7 Flashcards

1
Q

Parent drug of Digitoxin

A

Digoxin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Inhibits NA-K ATPase

A

Digoxin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Quinidine trough level

A

1 hour after last dose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Tacrolimus trough level

A

5 minutes before next dose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Metabolism of quinidine

A

n-acetylation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Metabolite of quinidine

A

N-acetylprocainamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Parent drug of procainamide

A

Quinidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What has anticholinergic and cardiac effects

A

Disopyramide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Undergoes Dealkylation

A

Lidocaine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

For gram-negative

A

Aminoglycosides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

For gram-positive

A

Vancomycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Ototoxicity, Nephrotoxicity, and Red Man syndrome

A

Vancomycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Drug method: chromogenic and immunoassays

A

Vancomycin and Aminoglycosides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Metabolite: Primidone; Parent drug:

A

Phenobarbital

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Liquid form of Phenytoin:

A

Fosphenytoin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Other name: Dilatin

A

Phenytoin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Other name: Depakene

A

Valproic Acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Enhances GAB

A

Valproic Acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Inhibits Lamotrigine

A

Valproic Acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Decreases motor complex

A

Ethosuximide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Reduced half-life when administered with:
1. Phenobarbital
2. Phenytoin
3. Primidone
4. Carbamazepine

A

Felbamate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Elimination is higher in children and pregnant women

A

Levetiracetam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q
  1. For complex partial seizure
  2. Treats acute intermittent porphyria
  3. Parent drug that can’t be broken down
A

Gabapentin

24
Q
  1. Tonic clonic seizure
  2. Pro-drug
A

Oxcarbazepine

25
Metabolite: Licarbazepine
Oxcarbazepine
26
1. Partial seizure 2. Experiences the ff: confusion, stuttering, mild sedation, and paresthesia
Tiagabine
27
Pins & needles Change of taste
Topiramite
28
Other name: Tegritol
Carbamazepine
29
Manic depression
Lithium
30
Methods: ISE, FEP, or AAS
Lithium
31
Inhibits Thyroid Secretion
Lithium
32
Inhibits: catecholamines
Tricyclic Anti-depressant
33
Competes with Sodium and Potassium
Monovalent
34
Competes with Calcium and Magnesium
Divalent
35
1. Treats: Depression, insomia, extreme apathy, loss of libido 2. Blocks catecholamines
Tricyclic anti-depressant
36
Inclined with Parkinsonian syndrome
Tricyclic antidepressant
37
Suicidal attempt/tendecies
Clozapine
38
Recurrence bipolar, acute manic episodes
Olanzapine
39
Treats OCDs
Fluoxetine
40
Blocks serotonin
Fluoxetine
41
1. Suppresses host vs graft 2. Blocks IL-2
Cylcosporine
42
Marked affinity with RBC
Cylcosporine
43
1. Same action with cyclosporine but 100x stronger 2. Choliestasis
Tacrolimus (FK-506)
44
Method: High performance liquid chromatography-mass spectrophotometry
Tacrolimus
45
1. Antifungal
Sirolimus
46
Other name: Rapamycin
Sirolimus
47
Specimen of choice:whole blood
Sirolimus
48
Blocks: Lymphocyte
Mycophenolic acid
49
Metabolite of Mycophenolic acid
Mycophenolate acid mofetil
50
Parent drug of Mycophenolic acid
Mycophenolate mofetil
51
Blocks: Dihydrofolate reductase (enzyme) w/c inhibits DNA
Methotrexate
52
Reverses methotrexate:
Leucovorin
53
Treats leukemia and lymphoma in neonates
Busulfan
54
Treatment for asthma that blocks Phophodiesterase
Theophylline
55
Other name: Tylenol
Acetaminophen
56
Inhibits: prostaglandin cylcooxygenase
Acetaminophen
57
Inhibits: prostaglandin synthase
Aspirin