CELL 2 Flashcards

(27 cards)

1
Q

what is simple diffusion

A

molecules move down conc gradient

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2
Q

what is not required for simple diffusion (2)

A
  1. transport proteins
  2. input of en from
    a. ATP
    b. conc / electrochemical gradient
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3
Q

what kind of transport is channel mediated

A

passive

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4
Q

what happens in channel mediated transport (2)

A
  1. channel opens

2. ion moves through channel

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5
Q

what kind of transport is carrier mediated transport

A

passive

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6
Q

what happens in carrier mediated transport (3)

A
  1. ligand binds to binding site of carrier on one side of mem
  2. carrier re-orient so binding site faces other side of mem
  3. ligand released
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7
Q

what is active transport

A

molecules move up conc gradient

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8
Q

what does active transport require

A
  1. trasport proteins
  2. input of en from
    a. ATP
    b. conc / electrochemical gradient
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9
Q

PRINCIPLES OF DIFFUSION what is simple diffusion

A

passive movement of molecules through intermolecular spaces in mem

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10
Q

PRINCIPLES OF DIFFUSION what is simple diffusion not

A

passive transport of molecules through intermolecular spaces in mem

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11
Q

PRINCIPLES OF DIFFUSION what is energy that causes diffusion

A

energy of normal kinetic motion of matter

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12
Q

PRINCIPLES OF DIFFUSION what 2 properties of molecule determines if it can cross mem by simple diffusion

A
  1. solubility in lipid

2. size

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13
Q

PRINCIPLES OF DIFFUSION what diffuses more readily

A
  1. non polar molecules

2. smaller molecules

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14
Q

PRINCIPLES OF DIFFUSION what diffuses less readily

A
  1. polar molecules

2. larger molecules

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15
Q

PRINCIPLES OF DIFFUSION what is PM permeable to

A
  1. non polar + uncharged

2. polar + uncharged + small

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16
Q

PRINCIPLES OF DIFFUSION what is PM slightly permeable to

17
Q

PRINCIPLES OF DIFFUSION what is the PM impermeable to

A
  1. polar + uncharged + large
  2. ions
  3. polar + charged
18
Q

PRINCIPLES OF DIFFUSION why is there no limit to simple diffusion

A

does not involved fixed number of binding sites

19
Q

PRINCIPLES OF DIFFUSION what kind of process is simple diffusion

A

non-saturable

20
Q

PRINCIPLES OF DIFFUSION what is magnitude of concentration gradient

A

diff in conc of substance across 2 solutions

21
Q

PRINCIPLES OF DIFFUSION what 4 factors influence rate of simple diffusion

A
  1. magnitude of driving force / magnitude of conc gradient
  2. membrane SA
  3. membrane permeability
22
Q

PRINCIPLES OF DIFFUSION what is SA directly proportional to

A

rate of simple diffusion

23
Q

PRINCIPLES OF DIFFUSION what is concentration gradient directly proportional to

A

rate of simple diffusion

24
Q

PRINCIPLES OF DIFFUSION what does higher permeability translate to

A

higher rate of simple diffusion

25
PRINCIPLES OF DIFFUSION what 5 properties does mem permeability depend on
1. lipid solubulity of molecule 2. size of moleucle 3. shape of moelcule 4. temp 5. diffusing distance / thickness of mem
26
PRINCIPLES OF DIFFUSION what causes higher permeability
1. more lipid soluble 2. small 3. regular shaped 4. high temp 5. thin
27
PRINCIPLES OF DIFFUSION what causes lower permeability
1. less lipid soluble 2. large 3. irregular shaped 4. low temp 5. thick