Cell death Flashcards
(13 cards)
What are the ways individual cells can die?
Necrosis and apoptosis
Characteristics of necrosis
involuntary, toxic inflammatory and can release harmful chemicals into extracellular fluid
Characteristics of apoptosis
careful coordinated manner that minimizes damage to surrounding tissues
What is general cause of necrosis
injury and disease
What happens during necrosis? ex infection
uncontrolled release of antigens that trigger an inflammatory response
How does programmed cell death work
molecular pathways are triggered that cause careful breakdown, and there is careful digestion
When does apoptosis occur
development, viral infection, end of lifespan
True or False apoptosis leaves traces of damage on cellular landscape
FALSE
True or False? Formation of many physical features as well as brain development occurs via apoptosis
True
Describe the cytological changes due to apoptosis
DNA digested by nuclease, organelle broken down/digested, polymer broken down, cell shrinks
What are apoptotic bodies and what happens to them
cell contents sealed into small sacs, broken down, recycled or used to communicate
Fill in the blank: Both intracellular and extracellular induction of apoptosis involves the activation of proteins called _____
caspases
True or False? signal to induce apoptosis can occur from external source or from damage detected inside the cell
True, there are extracellular and intracellular signal