Cells W1

Question 1

types of glial cells?

Answer 1

oligodendrocytes
Schwann cells
microglia
astrocytes
ependymal cells

Question 2

oligodendrocytes features?

Answer 2

produce myelin
found in CNS
cover multiple axons

Question 3

Schwann cells features

Answer 3

produce myelin
peripheral cells
one axon each

Question 4

microglia features

Answer 4

tiny compared to other glial cells
respond to damage in brain - patrol and change function in response to environment
phagocytosis, communication with astrocytes, synaptic pruning, regulation of other CNS cell development

Question 5

astrocytes features

Answer 5

look like stars under microscope
regulate neurotransmission
coordinates responses with other CNS cells
maintain blood brain barrier integrity

Question 6

microglia appearance?

Answer 6

reduce size when sense damage (dot appearance, not branching shape)

Question 7

ependymal cells function?

Answer 7

produce and maintain CSF
cilia help circulate CSF
line ventricles

Question 8

how does myelin appear on a microscope?

Answer 8

dark circles around nerves

Question 9

what conditions cause loss of myelin and what does this result in?

Answer 9

Multiple Sclerosis
Guillain Barre syndrome
impairs signal conduction

Question 10

what does the blood brain barrier protect the brain from and why can this be a problem clinically?

Answer 10

protects brain from environmental toxins, makes it hard to design drugs as they must be able to cross the blood brain barrier

Question 11

which cells form the blood brain barrier

Answer 11

astrocytes
pericytes
endothelial cells