_____ from granule cells converge on Purkinje cells.
Parallel fibers
Midline cerebellar lesions impair _____.
coordination of stance, gait, posture, and equilibrium
Climbing fibers ascending in the _______.
inferior cerebellar peduncle
What are the 3 phylogenetic divisions of the cerebellum?
- the archicerebellum
- the paleocerebellum
- the neocerebellum
Where do parallel fibers come from?
internal granular cells
_____ cerebellar lesions impair coordination of stance, gait, posture, and equilibrium.
Midline (vermis)
What is the output of the spinocerebellum paravermis pathway?
the lateral decending tracts and RED NUCLEUS
In all zones, the climbing fiber input comes from the ____.
contralateral inferior olivary nucleus (ION)
Mossy fibers from varying sources excite _____.
granular cells
What happens when a simple spike and a complex spike occur in the same location?
an excitation occurring in an already depolarized cell --> fire together = wire together --> long term depression --> reduce the efficiency of this synapse bc this is INHIBITORY
The lateral pathways control _____ while the medial pathways are for ____.
lateral = extremities; medial = postural and balance control
What is the function of the vermal region?
- axial control
- posture
- locomotion
- gaze reflexes
What does the cerebrocerebellum pathway project to?
the VL (ventrolateral) nucleus of the thalamus
What is the output of the vestibulocerebellum pathway?
vestibular nuclei
This zone of the cerebellum has control of modulation of stretch and withdrawl reflexes.
the paravermis
The mossy fibers come into the cerebellum and innervate the ____.
granule cells
What cells in the cerebellar cortex are inhibitory?
- the Purkinje cells
- the inhibitory interneurons
What are the 3 problems with synergy?
3 Ds (ataxia):
- dysmetria
- decomposition of movement
- dysdiadochokinesia
Parallel fibers from ______ converge on Purkinje cells.
granule cells
This zone of the cerebellum has control of the axial skeleton, posture, locomotion, and gaze reflexes.
the vermis
Climbing fibers come from the _____.
contralateral inferior olivary nucleus (ION)
Name the cerebellar functional zone: the contralateral VA/VL thalamus (and red nucleus)
cerebrocerebellum pathway
Cerebellar lesions DO NOT produce _____ or _____ loss.
weakness or sensory loss
What is the function of the vermis?
- axial control
- posture
- locomotion
- gaze reflexes
Climbing fibers from the ION converge on the ____ cells.
Purkinje
What is the function of the vestibulocerebellum?
- axial control
- vestibular control (balance, eye movements)
____ from varying sources excite granular cells.
Mossy fibers
Climbing fibers are oriented _____ to the plane of the dendritic arbor.
perpendicular
What is the HANDS tremor?
Hypotonia
Ataxia (3 Ds)
Nystagmus
Dysarthria
Stance and Gait
(Intention) tremor
What directly innervates the Purkinje cells?
the climbing fibers