Ch. 36 Disorders of Neuromuscular Function Flashcards Preview

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Flashcards in Ch. 36 Disorders of Neuromuscular Function Deck (36)
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1

Which autoimmune disease lacks acetylcholine?

Myasthenia Gravis

2

What are the signs and symptoms of Myasthenia Gravis?

-Muscle weakness pronounced more proximal the distal parts
-Fatigue
-Ptosis (eyelid drooping)
-Diplopia (double vision)
-Potential for respiratory weakness
-Symptoms worsen throughout the day

3

What are the treatments for Myasthenia Gravis?

-Immunosupressive therapy
-Corticosteriod drugs
-Plasmapheresis
-Thymectomy

4

In myasthenia gravis, periods of stress can produce myasthenia crisis. When does myasthenia crisis occur?

-When muscle weakness becomes sufficiently severe to compromise ventilation

5

What is any primary disorder of the peripheral nerves called?

Peripheral neuropathy

6

Can peripheral neuropathy involve a single nerve or multiple nerves?

Both

7

What is single nerve peripheral neuropathy called?

Mononeuropathy

8

What is multiple nerve peripheral neuropathy called?

Polyneuropathy

9

What syndrome is the compression of the medial nerve?

Carpa Tunnel Syndrome

10

Is carpal tunnel syndrome a mononeuropathy or a polyneuropathy?

Mononeuropathy

11

What are signs and symptoms of carpal tunnel syndrome?

-Pain
-Parasthesia
-Numbness of the first two and one half digits of the hand
-Pain in the wrist and hand
-Decreased grip

12

What are carpal tunnel syndrome treatments?

-Avoid movements that cause pain
-Splinting
-Anti inflammatory meds
-surgery

13

Is Guillain Barre a mononeuropathy or a polyneuropathy?

Polyneuropathy

14

What syndrome is an autoimmune disorder which causes rapidly progressive limb weakness and loss of tendon reflexes?

Guillain -Barre Syndrome

15

What are the causes of Guillain-Barre Syndrome?

-2/3 report acute influenza like an illness prior to the disease
-Streptococcal infection has been linked along with other bacteria

16

Does Guillain-Barre Syndrome start at the feet and works its way up?

Yes

17

What are Guillain-Barre signs and symptoms?

-Progressive ascending muscle weakness or the limbs
-Paresthesia
-Numbness
-Symmetric Flaccid Paralysis

18

What may paralysis in Guillain -Barre Syndrome progress to involve?

Respiratory Muscles

19

Where do patients with Guillain-Barre Syndrome have pain?

-Shoulder
-Back
-Posterior Thigh

20

What is the treatment for Guillain-Barre Syndrome?

-High dose IV immunoglobulin therapy
-Plasmapheresis

21

What percent of Guillain-Barre patients make a full recovery?

80-90%

22

What common disorder of the basal ganglia is there in the elderly?

Parkinson Disease

23

What is Parkinson Disease cause by?

A reduction in dopamine

24

What are the cardinal manifestations of Parkinson Disease (Parkinsonism)?

-Tremor
-Rigidity
-Bradykinesia

25

What are nonpharmologic treatments for Parkinson Disease?

-Group support
-Education
-Nutrition
-Daily exercise

26

What are pharmacological treatments for Parkinson Disease?

Antiparkinson drugs to increase function of dopamine system

27

What disorder affects the upper motor neuron?

Multiple Sclerosis

28

What is the name of a demyelinating disease of the CNS?

Multiple Sclerosis

29

What are causes of Multiple Sclerosis?

-Genetics
-Living in northern latitude areas
-Low Vit D levels

30

What are manifestations of Multiple Sclerosis?

-Paresthesia
-Pain from spasticity
-Abnormal Gait
-Bladder and sexual dysfunction
-Vertigo
-Fatigue
-Speech disturbance