CH 5 Adverse Drug Effects and Drug Interactions Flashcards Preview

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Flashcards in CH 5 Adverse Drug Effects and Drug Interactions Deck (12)
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Type of drug interaction in which two agents combine to produce a summation response:

Additive effect


An undesirable and potentially harmful action caused by the administration of medication:

Adverse drug effect


A voluntary program that encourages health care providers and consumers to report suspected adverse effects directly to the FDA or the product manufacturer:

FDA Adverse Event Reporting System (FAERS)

By law, reports received by the manufacturers are forwarded to the FDA to be added to the computerized information database.


In some drug inserts, a requirement by the FDA that warns prescribers that the drug carries a risk for serious or fatal adverse effects:

Black box warning


A hyperresponse of body defenses to a particular drug that may result in a diverse range of patient symptoms:

Drug allergies


Occurs when a medication interacts with another substance such as another drug, a dietary supplement, an herbal product, or food that is taken concurrently with the medication, and the drug's actions are affected:

Drug interaction


Unpredictable and unexplained drug reaction:

Idiosyncratic response


Drug-induced hearing impairment:



Determination of whether the risks from a drug outweigh the potential benefits received by taking the medication:

Risk-benefit ratio


Types of drug effects that are less serious than adverse effects, are predictable, and may occur even at therapeutic doses:

Side effects


Type of drug interaction in which two drugs produce an effect that is much greater than would be expected from simply adding the two individual drugs' responses:

Synergistic effect


Agents that cause birth defects: