Ch6 LET and RBE Flashcards

1
Q

Electromagnetic waves can break ___

A

Chemical bonds

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2
Q

What is particulate radiation

A

Emission of energized particles from the nucleus during radio active decay

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3
Q

What is excitation

A

Raising of a electron WITHOUT the ejection of an orbital electron

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4
Q

What is Ionization

A

Removal of an electron resulting in a ion pair

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5
Q

In ionization what charge is the newly freed electron

A

Negative

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6
Q

What energy does modern equipment use (Mv)

A

4-25 MV energy

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7
Q

Ionizatioan results in the ___ ___ of a radiation beam

A

biological effictiveness

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8
Q

Electromagnetic and particulate both (2)

A
  • Propel energy through space
  • Travel at the speed of light
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9
Q

Electromagnetic particles consists of

A

Photons

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10
Q

Electromagnetic have a ___ penetrability

A

Higher

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11
Q

Electromagnetic examples (3)

A
  • Radiowaves
  • Microwaves
  • Infrared
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12
Q

Photons have no (2)

A
  • Mass
  • Charge
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13
Q

Particulate particles can be

A

can be charged or uncharged

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14
Q

Particulate have a ___ penetrability

A

Lower

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15
Q

Examples of Particulate particles (2)

A
  • Alpha particles
  • Beat particles
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16
Q

What does LET measure?

A

The rate at which energy is transformed from souce to tissue

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17
Q

Densely ionizing has ___ LET

A

High

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18
Q

Sparsely ionizing has ___ LET

A

Low

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19
Q

Examples of densely ionizing particles

A

Alpha particles and neutrons

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20
Q

Examples of low LET rays

A
  • Xray
  • Gamma ray
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21
Q

LET Alpha particle
- Charge
- AMN
- LET

A
  • 2
  • 4
  • Highest
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22
Q

LET Neutron
- Charge
- AMN
- LET

23
Q

Direct interatction is more likely with ___ LET radaition

24
Q

What is the principle interaction in the body

A

Radiolysis of water

25
Alpha particles consists of
2 protons and 2 neutrons
26
LET Proton - Charge - AMN - LET
- 1 - 1 - High
27
Alpha particles are emmitted during the decay of
radionuclides
28
Direct interactions provide kinetic energy that can (2)
- Disrupt the atomic structure - Produce biological change
29
Direct interactions results from
Ionization or excitation of the target
30
Examples of high LET particles (3)
- Protons - Electrons - Neutrons
31
Direct action produces damage by
Direct ionization of the critical target
32
X-rays and gamma rays produce ___ ionization
Indirect
33
X-rays and gamma rays do not produce ___ and ___ damage themselves
- Chemical - Biological
34
Ionization of water and the formation of __ and __ ion pair. AND the formation of __/__ free radicals are extremely reactive
- H+ and OH- - OH/H
35
The major factor of damage is the ___, Via ___
OH radical via indirect action in the cell**.
36
Does indirect action or direct action have a greater probability of radiation damage? Why?
- Indirect action - there is more water in the body than any other components. body is 80% water & chances of spreading is more.
37
what does LET stand for?
linear energy transfer
38
Indirect interactions primarily occure through ionization of ___
water
39
Indirect interactions produce
Free radicals
40
Define Ion
Atom or molecule that is electrically charged because it has lost an electron
41
Define free radical
Fragment of an atom or molecule that has a unpaired electron in the outer shell making it highly reactive
42
Define LET
Rate at energy is deposited, as a charged particle travels through matter, by a particular type of radiation
43
LET is dependant on (2)
- Mass - Charge
44
Relative biologic effect is based on
differing rates of energy loss
45
Equal ___ of radiation differing in LET, produces ___ ___ of the same ___ ___
- Doses - Varying degree - Biologic responce
46
What is "Relative" Biological Effect
The ability of different types of radiation to produce the same biological responce
47
RBE= the comparison of a dose of __ ___ to the dose of ___ kev x-ray that produces the ___ ___ response
- Test radiation - 250 - Same biologic
48
Different "doses" of differing LET radiation will produce the
SAME DEGREE of a biologic effect.
49
different LET type radiation will produce the same degree of biologic effect but
at different doses
50
RBE formula
(Dose) of 250 Kev / (Dose) of test radiation
51
Standard formula
(Dose) of 250 Kev / 1.0
52
RBE geater than 1.0 indicates
Higher LET
53
RBE - 1.0 - 1.5 - 2.0
- Same effect -50% higher RBT - 100% higher RBT (Double effect)