Chap 29 Flashcards
(50 cards)
Homeoboxes
Genes that control expressions of other genes during development
General Properties of Development
A. Proceeds from simple, undifferentiated style to more complex, differentiated condition
B. Based on regulation of gene activity
Epigenetic
Gene effects only occur through interaction with the environment
Exhibits equipotentiality
Gets some developmental outcome from a variety of different starting conditions
Is Life Long
Ends in senescence = breakdown of the body in old age
What is Senescence?
Due to accumulation of free radicals from metabolism
What are Antioxidants?
Eliminates free radicals
Human Embryonic Development: Embryonic Period (0-2 months)
. Fertilization
A. Usually occurs within 24 hrs of ovulation
B. Usually occurs in Fallopian tubes
C. Requires capacity
Removal of enzymes inhibitors on head of sperm (acrosome) to allow penetration of egg membrane
Cleavage
Cell divisions with no overall increase in size
A. Occurs within Fallopian Tube, and within 24-30 hrs post-fertilization
B. Monozygotic (identical) twinning may occur here
Dizygotic twins
Non-identical resting from fertilization of > 1 egg
A. Results in morula comprised of blastomeres
Blastocyst Formation
A. Occurs approx. 5-7 days post-fertilization
B. Occurs in Fallopian tube, prior to entry into uterus
C. Morula enlarges and becomes hollow ball of cells
Trophoblast
Outer layer of cells (eventually becomes placenta)
Blastocoele
Hollow inner cavity of blastocyst
Inner cell mess
Embryonic tissue
Implantation
A. Occurs approx. 7 days post-fertilization
B. Blastocyst attaches to endometrium
* Trophoblast is site of attachment
Gastrulation
A. Occurs during remaining portion of embryonic period
B. Inner cell mass folds in on itself (=blastophere), creating 3 germ layers
Endometrium
Inner layer
Mesoderm
Middle layer
* gives rise to all structures of the muscular, skeletal, and cardiovascular systems
Ectoderm
Outer layer
- gives rise to all structures of the nervous system, plus skin and hair
- Coelom also forms
Membrane lined body cavity
Peritoneum and pleura
Formation of Embryonic Membranes:
What is a Yolk Sac?
Site of fetal blood formation, also provides some nourishment
Amnion
Surrounds embryo, keeps amniotic fluid in place
Amniotic fluid
Acts as a shock absorber
Chorion
Formerly the trophoblast become the placenta