Chap 80 Takayasu Flashcards Preview

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Flashcards in Chap 80 Takayasu Deck (10):
1

What is Takayasu's?

immune arteritis causing inflammation of aorta, its major branches, and pulmonary arteries.

2

What are proposed aetiologies of Takayasu?

genetic (HLA-Bw52)
immune mediated (cell and antibody)

3

What is histology of TA?

panarteritis (3 layers) with skip area
excessive ground substance in intima

4

What are clinical features of TA?

claudication (UE>LE)
diminished pulses
MSK symptoms
constitutional symptoms
H/A
CVI symptoms'
HTN common

5

What are findings on duplex?

thickened wall

6

Describe the1994 Tokyo international conference angiographic classification for TA?

Type I aortic arch branches alone
type II ascending, arch, branches
Type III ascending, arch branches and descending

7

Describe the1994 Tokyo international conference angiographic classification for TA?

Type I aortic arch branches alone
type II ascending, arch, branches
Type III ascending, arch branches and descending
Type IV abdominal aorta and branches
Type V entire aorta

8

What are features of active disease?

fever, myalgias
elevated ESR
vascular ischemia (claudication)
typical angio features

9

What is medical treatment?

glucocorticoids first line treatment
methotrexate, cyclophosphamide, azathioprine

10

What is invasive treatment strategies?

dont operate on active disease
endo poor results
bypass good patency