Flashcards in Drugs Deck (12):
What is MOA of ASA?
Binds to plt and prevents thomboxane production, which usually binds plt together
What is MOA of plavix?
Irreversibly dinds to PLT receptor P2Y12 (ADP receptor) on plt cell memebrane
This is important site for plt activation and corss linking
Name three thienopyridines.
What is MOA of IIbIIIa inhibitors?
Inhibit IIbIIIa receptor on plt and prevent plt aggregation and thrombus formation
Name three IIbIIIa inhibitors.
Abciximab, eptifibatide, tirofiban
What is MOA of ACEi?
Reduce activity of RAAS
Block conversion of AI to AII
What is MOA of beta blocker?
Block the endogenous action of catecholamines epi and norepi on adrenergic beta receptors
What is MOA of Heparin?
binds to enzyme inhibitor ATII causing conformational change that activates it.
What factors does ATIII inhibits.
What is the does for protamine?
1-1.5mg for every 100 IU of heparin
What is MOA of protamine?
binds to heparin or LMWH and forms ion pair inactivating heparin