Chapter 12 Flashcards
(39 cards)
Delusion
False belief that is strongly held despite contrary evidence
Schizophrenia
Severe psychological disorder characterized by negative symptoms such as emotional withdrawal and flat affect, and by positive symptoms such as hallucinations and delusions
Positive symptom
Hallucinations, delusions and excitatory motor behaviors
Negative symptom
emotional/social withdrawal and blunted effect
Concordance
Sharaing characteristics by both individuals of a pair of twins
Hypofrontality Hypothesis
idea that schizophrenia may reflect underactivation of the frontal lobes
Labotomy
Surgical separation of a portion of the frontal lobes from the rest of the brain, once used as a treatment for schizophrenia and many other ailments.
Dyskinesia
Difficulty or distortion in voluntary movements
Tardive dyskinesia
A disorder associated with typical antipsychotic use, and characterized by involuntary movements, especially of teh face and mouth
Supersensitivity psychosis
An exaggerated “rebound” psychosis that may emerge when doses of antipsychotic medication are reduced.
Chlorpromazine
An early antipsychotic drug that revolutionized the treatment of schizophrenia
Antipsychotic
Also called neuroleptic. Any of a class of drugs that alleviate symptoms of schizophrenia, typically by blocking dopamine receptors
Dopamine hypothesis
idea that schizophrenia results from either excessive levels of synaptic dopamine or excessive postsynaptic sensitivity to dopamine
Typical antipsychotic
also called typical neuroleptic. An antischizophrenic drug that shows antagonist activity at dopamine D2 receptors
Atypical antipsychotic
also called atypical neuroleptic. Antipsychotic drug that has primary actions other than or in addition to the dopamine D2 receptor antagonism that characterizes that typical antipsychotics.
Clozapine
An atypical antipsychotic
Phencyclidine (PCP)
“angel dust” anesthetic agent that is also a psychadelic drug. Makes many people feel dissociated from themselves and the environment.
Psychotomimetic
Drug that induces a state resembling schizophrenia
Ketamine
A dissociative anesthetic drug, similar to PCP, that acts as an NMDA receptor antagonist.
Glutamate hypothesis
Idea that schizophrenia may be caused in part by understimulation of glutamate receptors.
Depression
Psychiatric condition characterized by such symptoms as an unhappy mood; loss of interests, energy and appetite; and difficulty concentrating.
ECT Electroconvulsive shock therapy
Last resort treatment for unmanageable depression-strong electrical current is passed through the brain causing a seizure
Repetitive transcranial magnetic stimulation rTMS
Noninvasive treatment in which repeated pulses of focused magnetic energy are used to stimulate the cortex through the scalp
Monoamine oxidase (MAO)
An enzyme that breaks down monoamine neurotransmitters, thereby activating monoamine transmitter