chapter 13 Flashcards

1
Q

virion

A

single particle

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2
Q

viruses

A

more than one type of virus (HIV)

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3
Q

What was the first virus to be discovered?

A

TMV, tobacco mosaic

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4
Q

Characteristics of viruses

A

-do not divide
-can carry DNA or RNA but not both
-can perform reverse transcription
-cannot carry out metabolic pathways

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5
Q

mama virus and mimi virus

A

giant viruses

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6
Q

extracellular state

A

virion
-have a protein coat called a capsid that surrounds nucleic acid
-

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7
Q

nucleocapsid

A

combination of both capsid and nucleic acid together

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8
Q

intracellular state

A

capsid is removed and the virus exists as nucleic acid
-while in host cell, they only have a genome

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9
Q

Why do viruses only infect certain host cells?

A

due to the affinity of the viral surface and the complementary proteins on the host cell

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10
Q

generalists

A

infect many kinds of cells or many different hosts

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11
Q

What is the smallest virion?

A

bacteriophage MS2

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12
Q

Is a virion or bacteria bigger?

A

bacteria

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13
Q

What is the biggest animal virus?

A

smallpox

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14
Q

helical

A

capsid composed of capsomeres bound together in a circular fashion to form a tube around the nucleic acid

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15
Q

polyhedral

A

roughly spherical capsid

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16
Q

complex

A

many different shapes
rabies

17
Q

What is replication dependent on?

A

the hosts organelles and enzymes

18
Q

lytic replication

A

viral replication that results in death and lysis of the hosts
-attachment, entry, synthesis, assembly, release

19
Q

lysogenic replication of bacteriophages

A

the infected host cell grows and reproduces normally for generations before they lyse

20
Q

What are bacteriophages called in their inactive state?

A

prophages

21
Q

lysogenic conversion

A

phages carry genes that alter the phenotype of a bacterium from harmless to pathogenic

22
Q

Animal virus replication

A

same replication pathway as bacteriophages
results may vary due to the presence of an envelope, lack of cell wall

23
Q

In animal virus replication, where does DNA enter?

A

the nucleus

24
Q

In animal virus replication, where does RNA replicate?

A

in the cytoplasm

25
Q

What are the four types of RNA viruses?

A

ssRNA, retroviruses, dsRNA

26
Q

retroviruses

A

do not use genomes as mRNA,(HIV), use reverse transcriptase

27
Q

latency

A

phase where animal viruses that remain dormant in host cells

28
Q

What occurs during the penetration stage of the lytic cycle?

A

the phage injects its DNA into the host cell

29
Q

Synthesis stage of the lytic cycle

A

the phage causes the host DNA to break into small pieces and then uses the host to make new copies of its DNA

30
Q

Assembly stage (lytic)

A

the phage components are assembled into virions

31
Q

Release stage (Lytic)

A

the virons are released to infect other cells

32
Q

temperate bacteriophages

A

their DNA forms a circle that can replicate and be transcribed or can proceed to the lysogenic cycle after penetration

33
Q

Lysogenic cycle

A

the phage DNA integrates within the bacterial chromosome by recombination and the inserted phage DNA is a prophage
- when the bacterium reproduces, the prophage is copied

34
Q

induction

A

prophage is excised through the host chromosomes in a process called induction in the lysogenic cycle and after the prophage can enter the lytic cycle

35
Q

Which of the following proteinaceous subunits make viral capsid?

A

capsomere

36
Q

The enzyme lysozyme is critical for which of the stages of a bacteriophage T4 infection cycle?

A

entry and release