Chapter 13 Flashcards

(56 cards)

0
Q

Louis Pasteur did what?

A

Coined term virus

Latin for poison

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1
Q

Characteristic of viruses

A
Obligate intercellular parasite
Need host to multiple 
Submicroscopic 
Noncellular
Contain DNA or RNA
Protein coat 
Lack enzymes for ATP
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2
Q

Iwanowski and Beijernick

A

Discovered tabacco mosaic virus

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3
Q

Low leaflet and frosch

A

Discovered foot and mouth disease in cattle

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4
Q

Structure of viruses

A

DNA or RNA not both
Single or double stranded
Needs to enter host
Protected by capsid

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5
Q

What’s the capsid do?

A

Protein shell that surrounds nuclei acid

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6
Q

What is capsomere?

A

Sub unit of capsid that self assemble to form capsid

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7
Q

What is a naked virus mean?

A

No envelope

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8
Q

What is the envelope ?

A

Lipid structure that surround capsid

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9
Q

What are the spikes?

A

Project from envelope

Helps the virus adhere

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10
Q

Helical what is it??

A

Rod shape of the capsid

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11
Q

What is the polyhedral of the capsid?

A

20sided
3D appearance
Ex. Poliovirus, herpes, and adenovirus

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12
Q

What is the complex of the capsid

A

Capsid is polyhedral and contact tile sheath is helical

Ex. Bacteriophage and pox virus

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13
Q

What is the host range?

A

Spectrum of host cells a virus can infect
Depends on viruses requirement for multiplication
Must be chemically react with host receptors sites

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14
Q

What’s does the capsid do of a t-even bacteriophage ?

A

Stores nucleic acid

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15
Q

What does the contractile sheath of a t-even bacteriophage?

A

Penetrates and inject nucleiac acid

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16
Q

What is the tail fiber of bacteriophage do?

A

For attachment

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17
Q

What do the structure of t even bacteriophage of tail pins?

A

Penetration of cell wall

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19
Q

What are the steps of the lyric cycle in T4 viruses ?

A
  1. Attachment
  2. Penetration/Entry
  3. Biosynthesis
  4. Maturation
  5. Release
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20
Q

what is attachement?

A

uses the host cell’s receptor sites (tail fibers)

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21
Q

what is penetration/entry?

A

Biral nucleic acid is injected into the host cell

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22
Q

what is biosynthesis?

A

each viral componet is made using host’s metabolic machinery

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23
Q

what is maturation?

A

viral components are assembled

24
Q

what is release?

A

bacteria cell is full of virues, lyses, and dies

25
what is burst time?
time it takes from attachemetn to release | average time is 20-40 min
26
what is burst size?
number of viruses released per host cell | average is 200 viruses
27
viral multiplication in bacteriophage?
multiply in two ways | lytic and lysongenic
28
lytic cycle cells
end with lyse (death to host cell)
29
lysogenic cycle allows
host cell to remain alive
30
lysogenic cycle
incorporates a viral nucleic acid into host cell's phage remains inactive everytime host replicate virues is
31
what is adverse conditions do to lysogenic cycle?
can cause the lysogenic cycle to end and lytic cycle to begin
32
what is the steps in lysogenic cycle?
1. attachment 2. pentiration/entry 3. prophage created 4. bacteria divides with prophage
33
what is prophage?
combination of bacterial and viral nucleic acids | if prophage begins outside of bacterial cells, virus will being lytic cycle
34
how do you grow bacteriophage in the lab?
1. mix bacteria and virus in a soft agar solution and pour onto plate with solid agar 2. incubate at 38 degrees celcius 3. lawn of bacteria with plaque will apear
35
what is plaque?
were virus has killed bacteria
36
what is the process for multiplication in animal viruses
1. attachment 2. penetration 3. uncoating 4. biosythesis and assembly 5. release
37
growing animal viruses in the lab
in live animal ; some viruses can only exsist in animals study the immune system response
38
growing animal viruses in embryonic eggs
viruses is injected into fertilized egg viral growth is detected by death or damage to embryo used to make vaccines
39
how do you identify viruses?
cytopahtic effects serological tests nucleic acids
40
what is serological tests?
detects antibodies against viruses in a patient
41
what is nucleic acids?
uses PCR to obtain enough nucleic acids to identify
42
taxonomy of virues family genus species
family - virdae genus - virus species is common name of species
43
what are subspecies designated by?
number
44
example of taxonomy of viruses?
family ; herpesvirdae genus; herpesvirus species; human herpes virus subspecies; HHV-1, HHV-2
45
what is adenovirdae?
common cold viruses
46
what is poxvirdae?
small pox or cow pox
47
what is orthomyxovirdae?
influenza viruses A, B, and C
48
herpesviridae?
cold sore, chicken pox they are monoonucleosis
49
what is papvavirdae:
gential warts | cervic cancer
50
what is retrovirdae virus?
HIV
51
What are some extreme viruses?
ebola | causes fever, hemorrhaging and blod clotting
52
what is acute viral?
rapid onset of symptoms but not short lived | ex. influenza
53
what is latent viral infection?
virus remains asymtematic in host cell for long period of times ex. cold sores and shingles
54
what is persistant viral infections?
disease occurs over long period of time gennerally fatal Ex. HIV/AIDS
55
what are ways to prevent viruses?
vaccines---> ex. rubella | antiviral drugs --> AZT
56
what is prions?
proteinaceous infection particles cause neurolgical disease Ex. Mad cow disease