Chapter 13- Blood System Flashcards Preview

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Flashcards in Chapter 13- Blood System Deck (92):
1

% of blood that is cells

45

2

% of blood that is plasma

55

3

color

chrom/o

4

clotting

coagul/o

5

blood

hem/o ; hemat/o

6

bone marrow

myel/o

7

varied/ irregular

poikil/o

8

all of the cells are different sizes

poikilocytosis

9

iron

sider/o

10

round, globe

spher/o

11

patient's RBC are round

spherocytosis

12

clot

thromb/o

13

removal. carrying away

-apheresis

14

immature cell/ precursor

-blast

15

abnormal condition

-cytosis

16

protein

-globin ; -globulin

17

pertaining to the destruction of

-lytic

18

deficiency

-penia

19

attraction for

-philia

20

carrying transmission

-phoresis

21

putting electricity into the cell

electrophoresis

22

protein that stimulates the growth of WBC, given to cancer patients to stimulate WBC

CSF (colony stimulating factor)

23

method of separating serum proteins by electrical charge

electrophoresis

24

removal of plasma from blood by centrifuge, collected cells are transfused into the donor

plasmapheresis

25

deficiency in erythrocytes or hemoglobin

anemia

26

life span of erythrocytes

120 days

27

most common type of anemia

iron deficiency

28

bone marrow fails to produce adequate numbers of peripheral blood elements
lack of RBC, WBC, and platelets
excess bleeding, tachycardic, dizzy
pallor
immunosuppression and bone marrow transplant

Aplastic anemia

29

general term of many anemias in which the RBCs have a shortened life
generally feel unwell, jaundice, splenomegaly, hemoglobinuria, reticulocytosis, prostration

hemolytic anemia

30

most hemolysis occurs in the

spleen

31

all cell types are lost

pancytopenia

32

blood group incompatibility between mother and baby

hemolytic disease of the newborn

33

two abnormal RBC membranes

hereditary spherocytosis and elliptocytosis

34

spherical RBC

spherocytosis

35

megoloblastic anemia, lack of intrinsic factor from parietal cells in gastric mucosa. can't absorb B12, RBC cant mature, irreversible damage to nerves

pernicious anemia

36

pallor, glossitis, anorexia, ataxia, decreased sense of vibration and position, dementia, neuropsychiatric changes

pernicious anemia

37

megaloblastic anemia, deficiency of folic acid

folic acid deficiency anemia

38

dietary insufficiency, medications, malabsorption, overall feeling crappy

folic acid deficiency anemia

39

hypochromic, microcytic, anisocytosis, caused by underlying condition

iron deficiency anemia

40

cells are all different sizes

anisocytosis

41

fatigue, tachycardia, pallor, brittle nails, ice pica, smooth tongue, cheilosis

iron deficiency anemia

42

abnormal craving for something that isn't food

pica

43

inherited hemoglobinopathy, painful, crescent shaped RBC, recessive

sickle cell anemia

44

hypoxia, high altitude, acidosis, infections, dehydration

affect sickle cell anemia

45

jaundice, splenomegaly --> hyposplenism, pain, cardiomegaly, priapism,

sickle cell anemia

46

group of inherited disorders that effect synthesis of hemoglobin, hypochromic, microcytic RBC

thalassemia

47

Thalassemia prone in

Mediterranean, Middle east, southeast asia

48

excessive iron deposits throughout body, elevated liver functions, hepatomegaly, bronze hue, diabetes, cardiac failure, treatment by phlebotomy

hemachromatosis

49

general increase in RBC, hyperviscosity, phelebotomy or myelotoxic drugs as treatment

polycythemia vera

50

increase in RBC

erythremia

51

headaches, tinnitus, vertigo, epistaxis, bruising, upper GI bleed,sweating, spleno and hepatomegaly, bone tenderness

Polycythemia vera

52

inherited bleeding disorder secondary to clotting factor deficiency, easy bruising, hemorrhages, hemarthrosis

hemophilia

53

more common, not as severe as hemophilia, women who have had many miscarriages

Von WIllebrand's disease

54

Christmas Disease

Hemophilia B

55

bleeding under the skin, bigger than petichiae, multiple pinpoint hemorrhages and accumulation of blood under the skin

purpura

56

large bluish bruise

ecchymosis

57

small pinpoint bruises

petichiae

58

decrease in platelets after infection, <100,000

ITP (idiopathic thrombocytopenia purpura)

59

immature blood cells in the bone marrow and peripheral circulation producing neoplastic disorders, "blood cancer"

leukemia

60

lymphocytes predominate in leukemia

lymphocytic

61

myelocytes predominate in leukemia

myelogenous

62

chronic lymphocytic leukemia occurs in

older patients

63

acute lymphoplastic leukemia occurs in

childhood

64

diagnostic for chronic myelogenous leukemia

Philadelphia chromosome

65

bleeding, infection, gingival hypertrophy, joint pain, dyspnea, pallor, purpura, petechiae, stamtitis, lymphadenopathy

leukemia

66

leukemia treatment

bone marrow transplant

67

abnormal increase in granulocytes in blood, related to infectons

granulocytosis

68

caused by EBV, transmitted through saliva, long uncubation period,order antibody test, maculopapular rash, splenomegaly, very tired

mononucleosis

69

malignant tumor of the bone, malignancy of plasma cells, monoclonal protein in serum or urine, bone/spinal pain, pathologic fracture in 1/3, bleeding of nose and gums,

multiple myeloma

70

protein found in bones in multiple myeloma

benz jones protein

71

test detects antigen-antibody complexes on RBC membrane in vivo

antiglobulin test/ coomb's test

72

measures the primary phase of hemostasis, checks for platelet function,best single screening test for platelet function

bleeding time

73

normal bleeding time

<8 minutes

74

time required for venous blood to clot in a test tube

coagulation time

75

normal coagulation time

<15 minutes

76

sedimentation occurs when the erythrocytes clump or aggregate together in a column like manner

rouleaux formation

77

another more expensive, more specific test, measuring sed rate that indicatesd if there's an inflammation reaction going on

CRP (C reactive protein)

78

rate at which erythrocytes settle out of anticoagulated blood in 1 hour

erythrocyte sedimentation rate

79

percentage of RBC that goes hand in hand with hemoglobin, written in percentage

hematocrit (Hct)

80

hematocrit measure's RBCs ___

mass

81

main component of erythrocytes, vehicle of transportation for O2 and CO2,

hemoglobin

82

very variable, "high swing zone" in this cell measurement

platelet count

83

one-stage clotting test screening for coagulation disorders, detects deficiencies of intrinsic thromboplastin system, end stage liver disease, used to monitor heparin

platelet thromboplastin time, PTT

84

tests ability of blood to clot, protein produced in the liver for clotting of blood, depends on K,used to evaluate Heparin and Coumadin

Prothrombin time

85

determines the total number of RBC in a _____ of blood

microliter, cubic millimeter

86

examines different variations, abnormalities, size, shape, structure, Hb content, staining

RBC morphology

87

define the size and Hb content of RBC and consist of

RBC indicies
mean corpuscular volume
mean corpuscular hemoglobin concentration
mean corpuscular hemoglobin

88

individual cell size is best index for classifying anemias, expresses volume occupied by a single erythrocyte and measure in cubic micrometers,

MCV (mean corpuscular volume)

89

measurement of WBC in mm3, useful to severity of disease

WBC count

90

increase in one type of leukocyte

Leukocytosis . 11,000

91

less than 4000 WBC

leukopenia

92

increase in immature cells, significant infection or leukemia,

left shift