Chapter 157 - Tuberculosis and Infections with Atypical Mycobacterium

Question 1

MOTT are more often the cause of skin disease than M. Tuberculosis.
True or False

Answer 1

True

Question 2

MOTT has skin involvement but with no lymph node involvement (5)

Answer 2

M.Marinum
M.Ulcerans
M.Gordonae
M.Haemophilum
Fast growers MOTT

Question 3

Fast growers MOTT (3)

Answer 3

M. Fortuitum
M. Chenolae
M. Abscessus

Question 4

Painless nature of buruli ulcer is due to nerve damage and tissue destruction caused by toxin

Answer 4

Mycolactone

Question 5

Closely related to M. Tb but more common in individuals with underlying immunosuppression caused by Hodgkin disease, treatment for organ transplantation, or AIDS

Answer 5

M. Kansasii

Question 6

MC affected organ of M. Kansasii

Answer 6

Lung

Question 7

MC presentation of M. Scrofulaceum

Answer 7

Cervical lymphadenitis

Submandibular, submaxillary

Question 8

Pathogen of cervical disease with sinus formation that is indistinguishable from tuberculous scrofuloderma

Answer 8

Mycobacterium avium intracellulare

Question 9

Dimorphic inflammatory response consists of (2) usually observe in fast growers MOTT

Answer 9

1. Occurrence of PMN leukocyte microabscesses

2. Granuloma formation with foreign body type giant cells

Question 10

Can be treated with 
Rifampicin
Isoniazid
Ethambutol
Streptomycin

Answer 10

M. Kansasii

M. Intracellular Avium complex

Question 11

Can be treated with
Rifampicin
Ethambutol
Streptomycin

Answer 11

M. Ulcerans

Question 12

Can be treated with
Rifampicin
Ethambutol

Answer 12

M. Marinum

Question 13

Used to treat fast growers

Answer 13

Amikacin

Surgery

Question 14

Can be treated with

Rifampicin
Isoniazid

Answer 14

M. Scrofulaceum

Question 15

3rd most frequent pathogen after M. Tb, M. Leprae

Answer 15

Mycobacterium ulcerans

Question 16

Violaceous papule 2-3 weeks after inoculation secondary to trauma and water or fish/seafood related hobbies

Answer 16

Mycobacterium marinum

Question 17

Psoriasiform or verrucous plaque at the site of inoculation on hands, feet, elbows, knees

Answer 17

Mycobacterium marinum

Question 18

Atypical mycobacterium closely related to M. Tb

Answer 18

M. Kansasii

Question 19

Occurs in individuals with underlying immunossuppression such as organ transplantation, Hodgkin disease, and AIDS

Answer 19

M. Kansasii

Question 20

Most commonly affected organ of M. Kansasii

Answer 20

Lung

Question 21

M. Kansasii may manifest as

Answer 21

Sporotrichoid
Carpal tunnel syndrome
Joint disease
Periorificial cutaneous infection

Question 22

Unilateral cervical lymphadenitis in children of 1-3 years old with no constitutional symptoms

Answer 22

M. Scrofulaceum

Question 23

Cervical lympahdenitis with sinus formation causing lung disease and osteomyelitis

Answer 23

Mycobacterium avium intracellulare

Question 24

Painful red infiltration at site of inoculation with no constitutional symptoms

Answer 24

Fast growing mycobacterium

Question 25

Disseminated disease of fast growers occur in

Answer 25

Hemodialysis

Immunocompromised