Chapter 172- Chancroid Flashcards

1
Q

Acute ulcerative disease localized at the anogenital area and associated with inguinal adenitis or bubo

A

Chancroid

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2
Q

Chancroid manifests as painful soft ulcers with ragged undermined margins that develops ___ weeks after inoculation

A

1-2

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3
Q

Diagnostic test for chancroid

A

Nucleic acid amplification test

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4
Q

Reservoid in all reported outbreaks of chancroid

A

Low class prostitutes

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5
Q

Reduces risk of chancroid transmission

A

Male circumcision

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6
Q

Chancroid ulcer is an important risk factor for

A

Heterosexual spread of HIV

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7
Q

Duration of infectivity is estimated to be ___ for women

A

45 days

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8
Q

Transmission rate from males to females is __% and females to males is __%

A

70%/sexual act

?

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9
Q

Incubation period of chancroid

A

3-7 days

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10
Q

Vesicles are commonly seen in chancroid.

True or False

A

False, not seen

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11
Q

Chancroid ulcers in males are found in (3)

A

Prepuce
Frenulum
Glans

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12
Q

Meatus and shaft of penis and anus are involved more commonly in chancroid.
True or False

A

Less commonly

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13
Q

Chancroid ulcers in females are found in (4)

A

Fourchette
Labia minora
Vestibule

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14
Q

Painful inguinal adenitis (bubo) occurs in __% of patients within a few days to 2 weeks

A

50

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15
Q

Buboes are bilateral and may rupture spontaneously.

True or False

A

False, unilateral

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16
Q

In industrialized countries, isolated painful chancres are most likely caused by ___

A

Herpes simplex virus

17
Q

In a high percentage of ulcers, no pathogen can be isolated but coninfections with syphilis or herpes simplex are not uncommon

A

Ulcus mixtum

18
Q

Lesion that becomes confluent, spreading by extension and autoinoculation in the groin or thigh

A

Large serpiginous ulcer (ulcus molle serpiginosum)

19
Q

Rapid and profound destruction of tissue caused by superinfection with fusospirochetess

A

Phagedenic chancroid

Ulcus molle gangrenosum

20
Q

Small ulcer that resolves spontaneously in a few days ff by regional lymphadenopathy in 2-3 weeks

A
Transient chancroid
(Chancre mou volant)
21
Q

Multiple small ulcers in follicular distribution

A

Follicular chancroid

22
Q

Single lesion extends peripherally and shows extensive ulceration

A

Giant chancroid

23
Q

Granulomatous ulcerated papule that resemble dinivanosis or condyloma

A

Papular chancroid

Ulcus molle elevatum

24
Q

3 classic etiologic agents for ulceration

A

H. Ducreyi
T. Pallidum
Herpes simplex

25
Low sensitivity and specificity hence not recommended for diagnosis
Chancroid
26
Most frequent complaint of chancroid
Local pain
27
Reinfections are impossible. | True or False
False, possible hence use condoms properly
28
WHO/CDC recommendation for chancroid (4)
Azithromycin 1g PO in single dose Ceftriaxone 250mg IM in single dose Ciprofloxacin 500mg PO BID for 3 days Erythromycin 500mg PO QID for 7 days
29
In pregnancy, treatment of choice is
Ceftriaxone 250mg IM in a single dose
30
Risk factor for reinfection and Tx failure for chancroid (2)
HIV infection | Lack of circumcision
31
If patient complains of one or more small blisters with history of recent blisters, treat for
Herpes
32
If patient complains of isolated small ulcer and painful matted gland, treat for
LGV Chancroid Syphiliis
33
If patient complains of ulcer, treat for
Syphilis | Chancroid
34
Sexual contact of patients within __ days should be examined and treated regardless of whether symptoms of disease are present
10 days
35
H. Ducreyi is considered as a cause of chronic limb ulcers in adults and in children. True or False
True
36
Treatment for suppurative nodes
Punctured with a large syringe, emtered laterally, to prevent spontaneous rupture and sinus tract formation Not incised