Chapter 17 - Final Exam Flashcards
(44 cards)
Overweight/Obesity Nomenclature
1980's - ideal body weight mid 80's - desirable body weight 1995 - healthy body weight overweight - weight level associated with higher risk for disease, disability, and death obesity - degree of overweight
Obesity Education Initiative (NIH)
developed BMI (kg/m^2) approximates body fat (important indicator of health) overweight = BMI of 25.0-29.9 obese = BMI of over 30
Exceptions for use of BMI
BMI measures do not accurately represent healthy weights of people who are:
athletes with ^ muscle mass
individuals with low muscle mass
individuals with large, dense bones
Effects of Obesity
^ body weight = ^ morbidity
hypertension, stroke, dyslipidemia, coronary heart disease, type II diabetes, gallbladder disease, osteoarthritis, sleep apnea, cancer, orthopedic problems
Etiology of Obesity
Overweight and obesity have multiple causes
more cal consumed than ecpended
Leptin-Ghrelin-Neuropeptide Y (NPY)
stimulates appettitie
Leptin defcient children
absence of pubertal growth spurt with final adult height of subject reduced
respond to leptin therapy
reduced energy intake up to 84%
Leptin and obesity
plays large part in causing obesity if insufficient, but can get treatment
administration of leptin directly to hypothalamus
Central Leptin Gene therapy
Long-term expression
low immunogenicity
Leptin Conclusion
techniques that augment hypothalamic leptin are likely to curtail obesity and ailments associated with the metabolic syndrome
Nutrition Interventions for Obesity
realistic goals: loss of 0.5-1.0 lbs/wk
meal plan: readily available and enjoyable foods
anticipate/solve potential weight-management problems
stress management: other than eating to deal
regular exercise
cultivate self image
behavioral change for lifetime
Metabolic syndrome
spectrum of metabolic abnormalities that ^ risk of cardiovascular disease and type 2 diabetes
20-30% of adults
diet therapy: weight reduction with diet and exercise (diets high in antiox-rich fruits and veggies, whole grains, fiber, low-fat dairy)
Cardiovascular disease (CVD)
diseases related to heart/blood vessels
associated with atherosclerosis-consists of; coronary heart disease, cerebral vascular disease, blood vessels in legs
over 82 mil adults
#1 cause of death in US adults
Characteristics of CVD
Atherosclerosis - hardening of arteries
due to plaque build up, increases risk of stroke (lack of O2 to brain)
Etiology of Atherosclerosis
multifactorial; chronic arterial inflammation, thickening as result of cell damage, formation of fibrous plaque at point of injury, calcification of fibrous plaque
Effects of CVD
build up of plaque leaves less room for blood flow, resulting in:
decreased blood flow to heart, reduced energy, decline in organ function, inability to perform ADL (activities of daily living), shortness of breath, chest pain (angina)
Medical Nutrition Therapy for CVD
Therapeutic Life Changes (TLC):
recommended for high-risk individuals
diet/lifestyle change is cornerstone of therapy
Nutrition Interventions for Coronary Heat Disease CHD
national cholesterol education program:
total fat intake from 25-35% of cal
daily cholesterol or eq to 200 cal/d in PA
Diabetes Mellitus
Def: fasting blood glucose levels ≥ 126 mg/dL 25.6 mil people in US < 1% of pop. in 1960 ~ 11.3% of pop. in 2010 79 mil have "prediabetes"
Type 1 Diabetes
progressive autoimmune disease pancreatic b (beta) cells destroyed daily insulin injections required
Type 2 Diabetes
insulin resistance
most common type
Cost of Diabetes
$174 billion: total costs of diagnosed diabetes in US in 2007
- $116 billion for direct medical costs
- $58 billion for indirect costs (disability, work loss, premature mortality)
Etiology of Diabetes
Type 2 caused by insulin resistance combined with insulin insufficiency
insulin: hormone produced by pancreatic b-cells, facilitates passage of glucose into cells
Insulin Resistance
what is it: condition where cells “resist” the action of insulin in facilitating the passage of glucose into cells
contributors: abdominal obesity, decreased PA, genetic predisposition