Chapter 3 - E1 Flashcards

(30 cards)

1
Q

Products of Mitosis

A

Produces 2 identical daughter somatic cells

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2
Q

What is included interphase?

A

G1, G0, S, and G2

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3
Q

Characteristic of G1?

A

High levels of gene expression

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4
Q

S (synthesis phase) characteristics

A

Where DNA replication occurs

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5
Q

G0 characteristics

A

Where cells express their genetic information and carry out normal function but do not replicate

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6
Q

G2 characteristics

A

Preparation for cell division

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7
Q

M phase substages

A

Prophase
Metaphase
Anaphase
Telophase/Cytokinesis

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8
Q

Karyokinesis

A

Equal partitioning of the chromosomal material into the nuclei of 2 daughter cells

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9
Q

Cytokinesis

A

Equal partitioning of the cytoplasmic contents into 2 daughter cells

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10
Q

Centromere

A

Specialized DNA sequence on each chromosome where sister chromatids are joined together

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11
Q

What occurs in Prophase?

A

Chromosome condensation begins
Centrosomes migrate toward opposite poles
Microtubules extend to form a partial mitotic spindle

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12
Q

What occurs in Prometaphase?

A

Centrosomes extend microtubules that attach to kinetochores of chromosome centromeres
Chromosomes move toward the middle

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13
Q

What occurs in Metaphase?

A

Chromosomes are fully condensed and are aligned so that the sister chromatids lie on either side of the metaphase plate
- Kinetochore, nonkinetochore, and astrial tubules are fully extended

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14
Q

What occurs in Anaphase?

A

Sister chromatid seperation trhgouh the breakdown of cohesin

Daughter chromosomes move toward opposite poles

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15
Q

What occurs in Telophase/Cytokinesis?

A

Cells are elongated

Cytokinesis diveds the cytoplasm to create 2 new cells

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16
Q

How to spindle fiber microtubules elongate?

A

Through the addition of tubulin subunits

17
Q

Where do the - and + ends anchor?

A
  • end anchors at the centrosome

+ end grows away from the centrosome

18
Q

What is the role of cohesin?

A

Coats sister chromatics (most concentrated near the centrosomes)
Hold the chromosomes together to reduce the pull of the kinetochore

19
Q

Definition of disjunction

A

Seperation of chromosomes

20
Q

What are the four checkpoints?

A

G1, S, G2, and Metaphase

21
Q

Products of Meiosis

A

4 haploid gametes

22
Q

Events that occur in Meiosis 1

A

Homologous chromosomes pair
Crossing over occurs
Segregation of the homologous chromosomes (reduces it to haploid number)

23
Q

Events that occur in Meiosis 2

A

Sister chromatids seperate

Produces 4 genetically distinct haploid cells

24
Q

What is SRY?

A

Sex determining region of the Y gene in human males

- inhibits femaleness

25
What is a Barr Body?
Inactivated X chromosome when too many X's are present | - Random X-inactivation hypothesis
26
What are kinesin motor proteins?
Use ATP hydrolysis to physically move toward the plus end
27
What are dynein motor proteins?
Move toward the minus end
28
Role of separase
Cleave the cohesin complex to promote chromatid seperation
29
Chiasma
Contact points between homologous chromosomes where recombination has already occurred
30
What does TDF do?
Stimulates transcription of genes needed for Wolffian duct development into male reproductive tissues