chapter 35 Flashcards
(28 cards)
pathogens
agents that cause diseases
immune system
limits many infections
innate immunity
animals immunity that is present before any exposure to pathogens and it is effective from the time of birth
adaptive immunity
vertebrates immunity that is developed after exposure to certain pathogens
phagocytosis
is the ingestion and breakdown of foreign substances including bacteria
neutrophils
circulate in the blood and are attracted by signals from infected tissues
macrophages
are found throughout the body
interferons
interfere with viral reproduction
complement system
consists of proteins that are activated by substances on microbe surfaces
natural killer cells (WBC)
cellular innate defenses in vertebrates
inflammatory response
pain and swelling is brought about by molecules released upon injury or infection
mast cells
release histamine which triggers blood sessile to dilate and become more permeable
lymphocytes
adaptive response relies on two types of these
T cells
lymphocytes that mature in the thymus
B cells
lymphocytes that mature in bone marrow
antigens
are substances that can elicit a response form a B or T cell
antigen receptor
recognition occurs when a B or T cell inks to an antigen. happens by these receptors
epitope
small accessible part of an indigenous that binds to an antigen receptor
humoral immune response
B cells and their antibodies help neutralize pathogens in the blood and lymph
antibody or immunoglobulin
protein that is released in solid form from B cell activation
cell-mediated immune response
T cells bind only to antigen fragments displayed or presented on a host cell
MHC (major histocompatibility complex)
molecules are host proteins that display the antigen fragments on the cell surface
antigen presentation
MHC transport the antigen fragments to the cell surface
clonal selection
once activated B or T cell undergoes multiple cell divisions to price a clone of identical cells