Chapter 4 - Psychopharmacology Flashcards

(48 cards)

0
Q

Neuromodulator

A

A chemical messenger that communicates with target cells more distant then the synapse by diffusing away from the point of release

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1
Q

Neurotransmitter

A

A chemical messenger that communicates across a synapse

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2
Q

Neurohormone

A

A chemical messenger that communicates with target cells at a great distance often by traveling through the circulation

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3
Q

Small-molecule transmitter

A

One of a group of chemical messengers that includes amino acids and amines

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4
Q

Neuropeptide

A

A peptide that acts as a neurotransmitter a Neuromodulator or a neurohormone

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5
Q

Amino acid

A

An essential component of proteins

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6
Q

Acetylcholine (ACh)

A

A major small-molecule neurotransmitter used at the neuromuscular junction, in the autonomic nervous system and the central nervous system

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7
Q

Acetylcholinesterase (AChE)

A

An enzyme that breaks down the neurotransmitter acetylcholine

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8
Q

Nicotinic receptor

A

A post synaptic receptor that responds to nicotine and ACh

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9
Q

Muscarinic receptor

A

A post synaptic receptor that responds to both ACh and muscarine

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10
Q

Monoamine

A

One of a major group of biogenic amine neurotransmitters including dopamine norepinephrine epinephrine and serotonin

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11
Q

Catecholamine

A

A member of a group of related biogenetic amines that includes dopamine epinephrine and norepinephrine

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12
Q

Indoleamine

A

One of a subgroup of mono amines including serotonin and melatonin

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13
Q

Monoamine oxidase

A

A enzyme that breaks down monoamines

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14
Q

L-Dopa

A

A substance produced during synthesis of catecholamines that is also administered as a treatment for Parkinson’s Disease

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15
Q

Dopamine

A

A major monoamine and catecholamines neurotransmitter implicated in motor control reward and psychosis

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16
Q

Norepinephrine

A

A major monoamine and catecholamines neurotransmitter

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17
Q

Epinephrine

A

One of the monoamine and carecholamine neurotransmitters also known as adrenaline

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18
Q

Serotonin

A

A major monoamine and indoleamine neurotransmitter believed to participate in the regulation of mood sleep and appetite

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19
Q

Glutamate

A

A major excitatory amino acid neurotransmitter

20
Q

Gamma-aminobutyric acid GABA

A

A major inhibitory amino acid neurotransmitter

21
Q

Adenosine CNS

A

A byproduct of adenosine triphosphate (ATP) that functions as a neurotransmitter

22
Q

Nitric oxide (NO)

A

A gas they performs a type of signaling between neurons

23
Q

Agonist

A

Substance that promotes the activity of a neurotransmitter

24
Antagonist
Substance that reduces the action of a neurotransmitter
25
Reserpine
A substance derived from a plant that depletes supplies of monoamines by interfering with the reputake of monoamines into the synaptic vesicles used to treat high blood pressure but often produces depression
26
Botulism
A fatal condition produced by bacteria in spoiled food in which a toxin produced by the bacteria prevents the release of ACh
27
Curare
A substance derived from Amazonian plants that causes paralysis by blocking the nictonic ACh receptor
28
Benzodiazepine
A major tranquilizer that acts as a GABA agonist
29
Barbiturate
A drug that produces strong sedation by acting as a GABA agonist used for amnesia and seizures
30
Reputake inhibitor
Substance that interferes with the transport of released neurotransmitter molecules back into the presumaptic terminal
31
Area prostrema
A brainstem area in which the blood barrier is more permeable that triggers vomiting in response to the detection of circulating toxins
32
Addiction
A compulsive craving for drug effects or other experience
33
Nucleus accumbens
A dopaminergic structure believed to participate in reward and addiction
34
Psychoactive drug
A drug that produces changes in mental processes
35
Caffeine
A stimulant drug found in coffee, tea cola and chocolate that acts as a antagonist to adenosine
36
Nicotine
A stimulant drug that is the major active component found in tobacco
37
Cocaine
A powerful addictive dopamine agonist derived from the leaves of the coca plant of South America
38
Amphetamine
A highly addictive drug that acts as a potent dopamine agonist
39
Methamphetamine
A variation of amphetamine that is cheaply produced and widely abused
40
Ecstasy (MDMA(
a close relative of amphetamine that produces its behavioral effects by stimulating the release of serotonin
41
Gamma-hydroxybutyrate (GHB)
An illegal liquid sedative that appears to affect the thresholds of release for a number of neurotransmitters -date rape body building
42
Morphine
A compound extracted from opium used to treat pain
43
Codeine
An opium derivative used medically for cough suppression and pain relief
44
Opiate
An active substance derived from the opium poppy
45
Endorphin
A naturally occurring Neuropeptide that is very closely related to opioids
46
Tetahydrocannabinol THC
The major ingredient in cannabis
47
Anandamide
A naturally occurring brain chemical that interacts with cannabinol do receptors