CHAPTER 4: THE CHEMICAL BASIS OF HEREDITY: CONCEPT OF GENE Flashcards
(29 cards)
s are the physical basis of heredity and it carries the genes
Chromosome
is a double helix strand that is composed of polymer of repeating nucleotides (phosphates and nucleoside)
deoxyribonucleic acid (DNA)
are the hereditary units or fragments/segments or portions of DNA
Genes
It is the genetic material in almost all organisms:
deoxyribonucleic acid (DNA)
- a central region of a prokaryotic cell that contains its DNA
Nucleoid
molecules capable of storing and transmitting biological information
Genetic material
Genetic material:
DNA
RNA
- genetic material of eukaryotes, prokaryotes & some viruses
DNA
- genetic material of some viruses
RNA
DNA AS GENETIC MATERIAL:
- Faithful replication
- Variation by mutation
- Storage of information
- Expression and translation of the information into action
Which of the following best describes a DNA molecule?
a. Double helix
b. Contains ribose
c. Made of amino acids
d. Contains uracil
a. Double helix
1953: _______ and ________- proposed the molecular structure
of the DNA
James Watson and Francis Crick
Structure of DNA:
- Double helix, as related to genomics, is a term used to describe the physical structure of DNA.
- It is composed of two linear strands that run opposite to each other, or anti-parallel, and twist together.
- Each strand has a backbone made of
alternating sugar (deoxyribose) and phosphate groups. - sugar-phosphate backbone”
CHEMICAL COMPONENTS OF THE GENETIC MATERIAL:
- phosphate group (PO4)
- sugar - pentose (five-carbon molecule)
- nitrogen base
Structure of DNA:
- Nucleotide bases / Nucleobases
- Deoxyribose (5-carbon sugar, pentose)
- Phosphate
Nucleotide bases / Nucleobases:
- Purines – adenine (A) and guanine (G)
- Pyrimidines – cytosine (C) and thymine (T)
and uracil (U)
- is the sugar component in DNA
Deoxyribose (5-carbon sugar, pentose)
- is the sugar component in RNA
Ribose
MOLECULAR STRUCTURE & CHEMICAL COMPOSITION OF DNA
a. Nucleotide
b. Nucleoside
c. Nucleobases
d. Complementary base pairs
e. Nitrogenous base
– building blocks of nucleic acids
Nucleotide
– sugar molecules and nitrogen bases
Nucleoside
– are parts of DNA and RNA involved in base pairing. They are complementary.
Nucleobases (Nucleotide bases)
Nucleobases found in DNA:
Cytosine (C), Guanine (G), Adenine (A), Thymine (T)
Nucleobase found in RNA:
Uracil (replaces Thymine in base pairing)