chapter 7 Flashcards

membrane (72 cards)

1
Q

does facilitated diffusion require energy

A

no

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2
Q

what molecules aid in facilitated diffusion

A

carrier or channel proteins

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3
Q

aquaporin

A

it is a hydrophilic channel in the protein that helps molecules get through by osmosis

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4
Q

how do carrier proteins bring molecules into the cell

A

carrier protein changes shape to transport solutes (glucose to pancreas membrane)

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5
Q

what is active transport

A

when a molecule goes against a concentrated gradient (low conc to high conc)

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6
Q

what does active transport require that passive doesn’t

A

active:
requires energy (ATP)
must be a carrier protein
allows cells to maintain different concentration levels

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7
Q

what is the sodium potassium pump

A

pumps 3 Na cations out of the cell and 2 K cations into the cell. Requires energy

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8
Q

binding of K+ triggers what?

A

release of phosphate

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9
Q

what is the role of a phosphate group in the S-P pump?

A

it allows the protein changes and releases Na+ out of the cell and removing the phosphate and returning to the original shape

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10
Q

the binding of Na+ stimulates what?

A

ATP hydrolysis

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11
Q

what side determines the charge of the cell membrane

A

cytoplasm side

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12
Q

what can cause the membrane to be potentially negative?

A

unequal distribution of ions across the membrane, more negative ions on the inside of the cell

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13
Q

movement of ions across the membrane is dependent on what two forces?

A

chemical force and electrical force

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14
Q

what is chemical force?

A

ions concentration gradient

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15
Q

what is electrical force?

A

effect of membrane potential on the ions movement

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16
Q

what is electrochemical gradient?

A

combined forces of chemical and electrical

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17
Q

net negative charge inside a cell and net chemical gradient favors what?

A

movement of Na+ into the cell

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18
Q

what is proton pump?

A

continually pushing protons against gradient from inside of the cell to the outside

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19
Q

the proton pump is used by which organisms?

A

plants, fungi, and bacteria

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20
Q

the sodium potassium pump is used by which organisms?

A

animals

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21
Q

is the proton pump active or passive transport?

A

active bc it requires energy

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22
Q

where does the proton pump get its energy for its transport

A

the ATP potential energy is stored in membranes to be used when need be

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23
Q

what is cotransport

A

the additional energy from the proton pump pushes the H+ and sucrose into the cell.

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24
Q

how is ATP involved in cotransport

A

ATP is indirectly providing the energy necessary for cotransport (sucrose)

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25
exocytosis
large molecules exited by fusion of molecules to the plasma membrane
26
endocytosis
the cell takes in new biological molecules and forming new vesicles from the plasma membrane
27
phagocytosis
cell engulfs a particle of food or bacteria via pseudopodium to form a food vacuole
28
pinocytosis
cell gulps droplets of extracellular fluid into tiny vesicles
29
how is food digested
lysosome
30
receptor mediated endocytosis
enables cells to acquire bulk quantities of specific substances
31
ligand
molecule that binds specifically to a receptor site of another molecule
32
familial hypercholesterolemia
inherited disease characterized by very high cholesterol levels in the blood
33
tonicity
the ability of a solution surrounding a cell to cause that cell to gain or lose water
34
free water
crosses selectively permeable membrane
35
bound water
attached to hydrophilic parts of the solute molecules (sphere of hydration)-doesn't cross membrane
36
osmosis
movement of water molecules across a selectively permeable membrane
37
does osmosis require energy
no
38
how does water move in a solute concentration
water moves from an area of lower to higher solute concentration
39
equilibrium
solute molecules continue to cross membrane but at a similar rate in both directions
40
Does diffusion require energy
no
41
what is diffusion
the movement of a substances down its concentration gradient by random thermal
42
what is passive transport
is one mechanism that moves molecules across cells
43
what is considered "the edge of life"
plasma membrane
44
what is selective permeability
allows some substances to cross more easily than other substances
45
are organelles selective permeable?
yes
46
fluid-mosaic model
currently the most accurate model to explain the structure of the plasma membrane
47
how does the membrane represent "fluidity"
composed of a fluid phospholipid bilayer
48
what allows cells to maintain unique internal environments
selective permeability of a plasma membrane
49
how does the membrane represent "mosaic"
proteins are embedded or attached to the phospholipid bilayer
50
what is the dynamically structured mosaic model
current model that emphasizes on mosaicism rather than fluidity. Membranes are more packed with proteins than originally thought
51
how are membranes held together
WEAK hydrophobic interactions
52
why does the plasma membrane need to be flexible
for things to be able to get through
53
why can some proteins move across the plasma membrane
some proteins can't move because they are rigidly attached to the cytoskeleton and some aren't so they are more free
54
what are the differences in saturated and unsaturated membranes
at low temps, saturated hydrocarbons solidify unsaturated hydrocarbons stay fluid
55
what prevents hydrocarbons from solidifying
double bonds
56
what is cholesterol's involvement in membranes
at low temps: keeps fluidity | at high temps: less fluid
57
why is fluidity important for membranes
need to be fluid for molecules to get through, but not too fluid to lose shape
58
how do enzymes move through membranes
they move laterally
59
which types of proteins reach both outsides of the membrane
both, integral and peripheral proteins
60
integral proteins
cross the plasma membrane (hydrophobic/philic regions)
61
peripheral proteins
attached to the inner surface of the membrane some times via integral proteins
62
how is the plasma membrane supported
attachments to cytoskeleton (microfilaments) on cytoplasmic side
63
what does the plasma membrane attach to on the extracellular side, via the protein
collagen fibers and proteoglycans (which are attached to fibronectin)
64
what are the 6 major functions of the membrane proteins
``` transport enzyme activity signaling transduction cell to cell recognition intercellular joining attachment to cytoskeleton and ECM ```
65
membrane carbohydrates
usually short-branched polysaccharides (15
66
glycolipids
lipids with carbohydrates covalently attached
67
glycoproteins
proteins with carbohydrates covalently attached
68
where are glycoproteins and glycolipids found
within membranes
69
How does a transmembrane glycoprotein become embedded within plasma membrane
components of these membranes are synthesized within the ER
70
Where are phospholipids and glycoproteins modified
Golgi
71
what molecules move easily through the plasma membrane and why
molecules are non-polar and hydrophobic. They don't need aid of membrane proteins
72
what molecules move difficultly through the plasma membrane and why
polar molecules because it is troubled in the hydrophobic environment