Chapter 7 - Capsules Flashcards Preview

Phar Subjects > Chapter 7 - Capsules > Flashcards

Flashcards in Chapter 7 - Capsules Deck (27):
1

Designed to provide prolonged release of the medication

Extended-Release

2

Formulated to dissolve under the tongue or in the mouth

Sublingual or buccal tablets

3

Are solid dosage forms in which medicinal agents and/or inert substances are enclosed in a small shell of gelatin

Capsules

4

Used in the extemporaneous compounding of prescriptions

Hard gelatin capsules

5

Empty hard gelatin capsule shells are made of:

Gelatin
Sugar
Water

6

Obtained by the partial hydrolysis of collagen obtained from skin, white connective tissues and bones of animals

Gelatin

7

Dried silica gel, clay and activated charcoal

Desiccant

8

Gelatin being a protein is digested and absorbed by what?

Proteolytic enzymes

9

Noninvasive procedure that entails the use of a gamma ray-emitting radiotracer incorporated into the formulation with a gamma camera coupled to a data recording system

Gamma scintigraphy

10

Provides information about the transit and drug release patterns of the dosage forma as well as the rate of drug absorption

Pharmacoscintographic evaluation

11

Two parts of hard gelatin capsule

Body and cap

12

Available for veterinary use

Larger capsules

13

Commonly used diluent or filler

Lactose
Myocrystalline cellulose
Starch

14

Assist the breakup and distributionof the capsule's contents in the stomach

Disintegrants

15

Commonly used disintegrants

Pregelatinized starch
Croscarmellose
Sodium starch glycolate

16

Produce particles ranging from about 50-1000 mm. 10 mg or greater drug dosage

Milling

17

Produce particles ranging from 1-20 mm

Micronization

18

Enhances flow properties

Lubricant or glidant

19

Commonly used lubricant

Silicon dioxide
Magnesium stearate
Stearic acid
Talc

20

Used for its waterproofing characteristics that can retard penetration by the gastrointestinal fluids and delay drug dissolution and absorption

Magnesium stearate

21

Facilitate wetting by the gastrointestinal fluids to overcome the problem

Surface-active agent

22

Do not interfere with the stability of the gelatin shells

Fixed or volatile oils

23

Mixtures of agents that have a propensity to liquefy when admixed

Eutectic mixtures

24

Are made of glycerin or a polyhydric alcohol

Soft gelatin capsules

25

Soft gelatin capsules may be prepared by:

Plate process
Rotary or reciprocating process

26

Containers for dispensing capsules

Tight
Well closed
Light resistant
Combination

27

Designed to pass through the stomach for drug release and absorption in the intestine

Enteric coated tablets