CHOLINERGIC AGONIST AND ANTAGONIST (EXAM2) Flashcards
what is the main function of an cholinergic agonist drug
they stimulate the parasympathetic nervous system
what drug do cholinergic agonist mimic
acetylcholine
what are the 2 receptors for cholinergic receptors
muscarinic
nicotinic
what are the types of cholinergic agonist
direct acting
indirect acting
direct acting cholinergic
acts on receptors to activate tissue response
target specific sites
indirect acting cholinergic agonist
inhibit action of enzyme cholinesterase
the effect of cholinergic agonist on the cardiovascular system
-ITS ALL PAARSYMPATHETIC
-decrease BP, HR
-vasodilation
-slow conduction of the AV node
cholinergic agonist and GI
-increase muscle tone, motility, peristalsis, and relax muscle sphincter
-active bowel sounds
cholinergic agonist and GU
-Increase urine output
cholinergic agonist and eyes
constriction
cholinergic agonist and lungs
bronchial constriction
increase in secretion
with cholinergic agonist what kind of cough is there
productive cough from the increase in secretion
Indirect acting cholinergic function
they inhibit the cholinesterase enzyme
-allow acetylcholine to accumulate at receptor sites
Indirect acting cholinergic effects
-muscle contraction
-increased muscle tone
-bronchial constriction
-bradycardia
-miosis
-increased GI motility
-promote urination
Cholinergic antagonist
the stop the effects of acetylcholine by occupying the acetylcholine receptors
