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Drugs 183 > Class #1 and 2 -history > Flashcards

Class #1 and 2 -history Flashcards

1
Q

Morphine also called

A

Laudanum

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2
Q

One of the first physician act?

A

Urine analysis

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3
Q

Bright yellow urine =

A

Excessive B12

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4
Q

White urine =

A

INfection

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5
Q

Brown urine =

A

Liver problem

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6
Q

Pink urine =

A

Food or bleeding

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7
Q

Life expectancy at the en of 1800s?

A

~47

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8
Q

CAUSE of reduce maternal mortality?

A

Penicillin during WW2

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9
Q

Canada life expectancy (2015)

A

Men 81

Women 85

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10
Q

Olderst human?

A

Jeanne Clment, 122 in france

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11
Q
  1. Life span vs

2. Life expectancy?

A
  1. Longest determined age (canada 117)

2. Statistical average an organism is expected to live based on: current age, sex, etc

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12
Q

1918-1919 what happened?

A

Flu, spanish influenza, grip.

30-50 millions death

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13
Q

How influenza kills?

A

Bacterial pneumonia b/c virus destroyed bronchial cells and bacteria invade the lungs.

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14
Q

Number of compound in urineÉ

A

147

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15
Q

Summerians had?

A

16 different beer recipes

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16
Q

Hippocrates successful cure (2)?

A

Night blindness with Ox(bovine) Liver, b/c contains a lot of vit.A and Crying babies: Poppy juice and flies excrements.

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17
Q

Dioscorides major work?

A

De Meteria Medica: Tome about plants.

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18
Q

Wormwood was used in? discovered by? Also discovered

A

Absinthe
Dioscorides
Saffron -> diuretic -> Passum

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19
Q

Pharmakon=

A

drug

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20
Q

Paracelcus invented? How?

A

ether as an anesthetic agent. Treating alcohol with acids

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21
Q

Paracelcus was against?

A

The doctrine of Humours

22
Q

Paracelcus said and valued?

A

All drugs are poison only depend on the {}. Valued experimentation and reasoning, one of the first.

23
Q

Doctrine of signature (Eg. mandrake root)

A

Ressembles human part, must be good for it. Mandrake root ressemble a human body.

24
Q

Plant remedies:

  1. Ipecac
  2. Aconite
  3. Foxglove (date of publication)
A
  1. Emetic
  2. Poison
  3. produced Lanoxin/digoxin (1785 - one of first medical articles)
25
William Withering did what?
Discover usefulness of foxglove.
26
% of children in Rep. Dem. Congo infected with malaria?
50%
27
SmallPox eradicated by?
vaccins
28
Polio 1.Worldwide cases in 2016? | 2. Eradicated in America in?
1. 37 | 2. 1991
29
Leprosy also called? 1. Is? 2. Treatments? 3. Number of cases?
Hansen's Diseases 1. . Bacterial infection 2. Multi Drug Therapy 3. 12m before today 200 000
30
Guinea Worm disease what? how to treat?
Nematode worm from drinking water. | Cheesecloth to filter water
31
Chagas Disease
Kissing bug parasite, Trypanzoma Cruzi, delayed Sx (10-20years), Insecticide spraying
32
Protozoal/fungal diseases
treatment of esophagus.
33
Anesthetics/sedative?
Librium (chlorodiazepoxide) | valium (diazepam)
34
Drug acceptance minimum improvement? Average improvement?
1. 30%, over placebo | 2. 50%
35
$ spend on precribed Rx in NA? Us take % of world precribed Rx? OTC?
320 billions 50% 40B NA, 3B Canada
36
Smelling salts?
Ammonium carbonate
37
Doctrine of signature invented by?
Jakob Bohme
38
Aspirin comes from?
Willow bark, but is syntisize from it.
39
Who: "listen closely to pt and they will tell you the Dx"?
Sir William Osler
40
Malaria: 1. Type of disease? 2. cases per year/death 3. Early cure? 4. New cure 5. MOst impact
1. PArasite 2. 120M, 1-2M 3. Quinine 4. Artemisin 5. DDT - insecticide, but discontinued b/c early broken egg in birds
41
Joseph Lister discovered?
Phenol, used as disinfectant and in 50s as bad breath and dandruff control, contained thymol and propofol. Was a pionneer in asepsie, were glove during operation.
42
Salversan of compound 606?
First drug brought up by rigorous studies, cured syphilis.
43
Federal Food Drug ans Cosmetic Act date of foundation?
1938
44
What did Dr. Frances Kelsey do?
Warn about Thalidomide and connected death to dietyl glycol in sulphanilamide solution
45
Evaluation a new Drugs?
Kaplan-Meier plot, calculate survival rate.
46
Lipinski rule of five?
No more 5 hydrogen bond donors NO more 10 hydrogen bond acceptors Molecular weight no more than 500
47
Cantharidine extracted from?
Spanish flies
48
Flower perinwinkle wileds?
Vincristine
49
Prescription drug sale 2016?
750B$
50
Excipients?
Not medicine in pills

Drugs 183 (13 decks)

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