Class 3

Question 1

Adaptive (Acquired) immunity is the _____ line of defense

Answer 1

the third

Question 2

Antibodies are produced by?

Answer 2

B cells

Question 3

Do T cells produce antibodies?

Answer 3

No

Question 4

T cells trigger and activate?

Answer 4

B cells

Question 5

B cells are also called

Answer 5

Humoral

Question 6

T cells are also called

Answer 6

Cellular

Question 7

Hypersensitivity

Answer 7

excessive or inappropriate immune response to an antigen that that results in disease or damage to the host

Question 8

Allergy, autoimmunity and alloimmunity are ________ reactions

Answer 8

Hypersensitivity

Question 9

Allergy

Answer 9

Harmful effects of hypersensitivity to environmental (exogenous) antigens

Question 10

Autoimmunity

Answer 10

disturbance in the immunologic tolerance of self antigens

Question 11

Alloimmunity

Answer 11

immune reaction to tissues of another individual. Transplant or blood transfusion.

Question 12

What type of immune reaction is IgE mediated and involves the degranulation of mast cells?

Answer 12

Type I

Question 13

What type of immune reaction is IgG/IgM mediated and involves antigen-antibody complex formation on the cell surface?

Answer 13

Type II

Question 14

What type of immune reaction is IgM/IgG mediated and involves complexes that are formed in circulation and later deposited in different tissues and can cause an immune reaction in numerous places?

Answer 14

Type III

Question 15

Type I, type II, and type III reactions all involve _____ cells

Answer 15

B cells

Question 16

what type of immune reaction is cell mediated?

Answer 16

Type IV is cell mediated and involves T cells

Question 17

An atopic reaction indicates:

Answer 17

a genetic predisposition

Question 18

What is an example of a Type II sensitivity reaction?

Answer 18

Hemolytic disease of the newborn

Question 19

Type II reactions are tissue specific, this means?

Answer 19

there is an immune response to proteins on only certain cell membranes

Question 20

Type III reactions are different that Type II reactions because Type III reactions are?

Answer 20

Not specific to a cell membrane, instead complexes are formed and circulate throughout the body

Question 21

Antigen Antibody complexes in Type III reactions are formed in the _________ and later deposited in_____?

Answer 21

formed in the circulation and are later deposited in vessel walls or extravascular tissue

Question 22

Example of type III hypersensitvity reaction

Answer 22

Systemic Lupus Erythematosus

Question 23

Common clinical manifestations of SLE?

Answer 23

Arthralgia and arthritis

Question 24

Primary Immunodeficiency is also called?

Answer 24

congenital immunodeficiency

Question 25

secondary immunodeficiency is also called

Answer 25

acquired immunodeficiency

Question 26

what is the clinical hallmark of immune deficiencies

Answer 26

the development of unusual or recurrent severe infections

Question 27

B cell (humoral) deficiencies cause?

Answer 27

recurrent and life threatening bacterial infections

Question 28

T cell (cellular deficiencies) cause?

Answer 28

viral, fungal, yeast and atypical microorganisms

Question 29

which type of cell deficiency is worse to have?

Answer 29

T cell deficiencies because T cells stimulate B cells!

Question 30

DiGeorge syndrome

Answer 30

partial lack of thymus

Question 31

Example of primary T cell deficiency

Answer 31

DiGeorge syndrome

Question 32

Chronic stress decreases...

Answer 32

the size of the thymus gland resulting in less resistance to infections and cancers

Question 33

chronic stress increases...

Answer 33

antibody responses causing increased allergy and autoimmune responses

Question 34

poison ivy and contact dermatitis are examples of?

Answer 34

a type IV (cell mediated) allergy (hypersensitivity)

Question 35

thrombocytopenia is an example of?

Answer 35

a type II autoimmune hypersensitivity

Question 36

systemic lupus erythematosus is an example of?

Answer 36

a type III autoimmune hypersensitivity

Question 37

Hashimoto's thyroiditis is an example of?

Answer 37

A type IV autoimmune hypersensitivity

Question 38

Hemolytic disease of the newborn is an example of a?

Answer 38

Type II alloimmune hypersensitivity

Question 39

transplant rejection is an example of?

Answer 39

A type IV alloimmune hypersensitivity

Question 40

type III hypersensitivity reactions are

Answer 40

systemic

Question 41

Type II hypersensitivity reactions only affect?

Answer 41

specific cells

Question 42

What type of Type I hypersensitivity reaction is atopic?

Answer 42

Anaphylaxis

Question 43

what is the most common clinical manifestation of SLE?

Answer 43

Arthralgia and arthritis

Question 44

immunity has the properties of?

Answer 44

specificity, memory, inducibility and self-tolerance

Question 45

Hypersensitivity

Answer 45

an altered immunologic response to an antigen that results in damage or disease to the individual.

Question 46

breakdown of self-tolerance causes

Answer 46

autoimmunity

Question 47

what does stress do to the thymus?

Answer 47

causes atrophy of the thymus resulting in less resistance to infections and cancers

Question 48

what effects does stress have on the antibody response?

Answer 48

it increases antibody response resulting in increased allergy and autoimmune responses