Flashcards in CNS-Alcohol Deck (5)
what are the acute effects of ethanol on the CNS system?
dose-dependent CNS depression (ˇ membrane excitability + ^GABAa & ˇ NMDA acivation)
ˇ myocardial contractility
ˇ anxiety, slurred speech, impaired judgement
toxic doses: CNS and respiratory depression.
what are the chronic effects of ethanol on the CNS system?
fatty liver->hepatitis-> cirrhosis ->liver failure
pancreatits & gastritis
how is ethanol eliminated from the human body?
>90% is metabolized by the liver (oxidation)
what is methanol, and how is it metabolized?
methanol metabolism -> formic acid -> blindness