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Flashcards in CNS infections Deck (88)
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1

What are the four questions that should be answered with CNS infections?

-Acute or chronic
-Etiology
-Work up?
-Treatment

2

What are the major non-infectious etiologies of CNS problems?

-Neoplasia
-Collagen vascular disease
-Meds

3

What is the best way to assess for infectious CNS infections?

Spinal fluid

4

What is the major confounding factor of spinal glucose levels?

Pts has DM

5

How do you assess spinal fluid glucose levels in the diabetic patient?

ratio of serum to CSF should be less than 0.6

6

What is the normal opening pressure of CSF?

50-195 in the lateral decubitus position

7

What commonly complicates CSF fluid samples?

Prior abx treatment

8

What is a high CSF opening pressure most commonly seen in? Why?

Cryptococcal meningitis
Occludes the arachnoid villi

9

india ink stain = ?

Cryptococcal neoformans

10

True or false: with elevated intracranial pressure from cryptococcus infx, doing an LP is both diagnostic and therapeutic

True

11

When is flow cytology useful with CSF samples?

Diagnosing lymphomas

12

What is xanthochromia?

Yellowish supernatant of CSF that is a result of RBC lysis, indicated the presence of oxyhemoglobin, methemoglobin, and bili

13

How long does it take for RBCs to breakdown in the CSF to cause xanthochromia? Why is this important?

2-4 hours
Means that a traumatic tap will not cause this--this is pathologic

14

What is the normal WBC count in CSF in children and adults?

Both 0-5 /mm^3

15

What are the three etiologies of elevated WBC in the CSF?

Meningitis
Encephalitis
Parameningeal focus

16

What is the formula for the true WBC in CSF?

Actual WBC - (WBC in blood x RBC in CSF/ RBC in blood)

17

What is pleocytosis?

Increased WBC in the CSF

18

What non-infectious condition can produce a transient CSF pleocytosis?

Seizures

19

White counts in CSF are usually highest in what type of infectious etiology?

bacterial

20

What WBC cell predominates with viral meningitis?

Mononuclear

21

What WBC cell predominates with bacterial meningitis?

PMNs

22

What WBC cell predominates with TB meningitis?

Mononuclear

23

What WBC cell predominates with cryptococcal meningitis?

Mononuclear

24

What is the WBC range for viral meningitis?

50-1000

25

What is the WBC range for bacterial meningitis?

1000-5000

26

What is the WBC range for TB meningitis?

50-300

27

What is the WBC range for cryptococcal meningitis?

20-500

28

What are the glucose levels with viral meningitis?

More than 45

29

What are the glucose levels with bacterial meningitis?

Less than 40

30

What are the glucose levels with TB meningitis?

Less than 45