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Flashcards in Diagnosis of HIV pts Deck (96)
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1

What are the cells that HIV can hide out in?

Memory CD4+ T cells

2

What indicates that transition from HIV to AIDS?

CD4 less than 200

OR

AIDS indicator disease

3

What happens to the viral load with HIV infection? How does CD4 count relate to this?

Peaks initially, then drops to a "set point"

CD4 count is the inverse of this

4

How well does the viral load correlate to the progression of HIV to AIDS

Correlates well

5

What is the viral cause of Kaposi's sarcoma? What are the s/sx of this?

HSV 8

erythematous macules on the posterior oropharynx

6

At what CD4 count are AIDS pts susceptible to pneumocystis?

Less than 200

7

At what CD4 count are AIDS pts susceptible to toxoplasmosis?

100

8

At what CD4 count are AIDS pts susceptible to Cryptococcosis?

100

9

At what CD4 count are AIDS pts susceptible to Kaposi's sarcoma?

Over 400

10

At what CD4 count are AIDS pts susceptible to MAC?

Less than 50

11

At what CD4 count are AIDS pts susceptible to CMV?

Less than 50

12

What is the prophylaxis for toxoplasmosis?

TMP-SMX

13

What is the source of MAC?

Water sources

14

Does recurrent bouts of pyogenic pneumonia diagnose you with AIDS?

Yes

15

What is the cause of hairy tongue leukoplakia?

EBV caused growth that does not scrape away

16

What has happened to the incidence and prevalence of HIV?

-Incidence lower
-Prevalence growing (people living longer)

17

In what high risk group is HIV incidence increasing? Which is declining?

MSM

IVDA is going down

18

What is the current strategy to target MSM population to prevent AIDS?

Preexposure prophylaxis

19

What ethnicity have the highest prevalence of HIV?

African Americans

20

What percent of people with HIV are unaware they have it? What percent of new infections are caused by people who don't know they have it?

20% ish don't know

50% of new infections from people who do not know they have it

21

What is the percentage of CD4 that is diagnostic of AIDS? What does this mean?

Less than 14%

This means that less than 14% of T cells are of the CD4 variety (the remainder being CD8)

22

What percent of newly diagnosed HIV have a strain that is resistant to ART?

15%

23

What are the first s/sx of HIV with initial infection?

Mono-like ssx
-Pharyngitis, rash, HA

24

What percent of patients with an EBV infection present with a rash?

Less than 5%

25

What percent of patients with initial HIV infection have aseptic meningitis?

24%

26

What percent of patients with an initial HIV Infection present with oral ulcers?

15%

27

What percent of patients with an initial HIV Infection present with genital ulcers?

10%

28

What is the viral markers followed for initial HIV infection?

p24 antigen

29

What is the first, second, and third rise in markers for HIV?

1. HIV RNA first
2. p24 antigen
3. HIV ab last

30

Why does p24 antigen decline when HIV ab rise?

HIV ab binds to p24