Coagulation Cliff Notes Flashcards
(20 cards)
Negative ristocetin test
Von Willebrand disease
Chronic nosebleeds (epistaxis) or bleeding with tooth extraction or surgery
Von Willebrand disease
Prolonged PT and PTT, low fibrinogen, positive D dimer or positive FDP
DIC
Prolonged PT, normal PTT
Liver disease, Coumadin therapy, factor deficiency (factor VII OR V, maybe X)
Prolonged PTT, normal PT, corrected with mixing studies
Factor deficiency ( VIII, IX X XI or fibrinogen)
Prolonged thrombin time
Afribrinogenemia or dysfibrinogenemia or DIC
Bleeding into joints (hemarthrosis)
Hemophilia a or B
Petechiae, purpura, or eccyhymoses
Low platelets or abnormal platelets
Bleeding from gums
Low platelets
Primary hemostasis
Platelets
Secondary hemostasis
Coagulation cascade
Prolonged PT
Factors V, VII, or X, fribrinogen or prothrombin (II), or Coumadin therapy
Prolonged PTT
Factors VIII, IX, XI, X or heparin therapy
Prolonged bleeding time, normal platelet count
Von Willebrand’s disease
Prolonged bleeding time, low platelet count
Idiopathic thrombocytopenic purpura (ITP), TTP, or chemotherapy
Prolonged PT, PTT, low fibrinogen
DIC
Positive D dimer
DIC, deep vein thrombosis, pulmonary embolism
Mixing studies, PT or PTT not corrected
Lupus anticoagulant
Mixing studies, PT or PTT corrected
Factor deficiency
Russell viper venom
Lupus anticoagulant
