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Flashcards in Coagulation Cliff Notes Deck (20)
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Chronic nosebleeds (epistaxis) or bleeding with tooth extraction or surgery

Von Willebrand disease

1

Negative ristocetin test

Von Willebrand disease

2

Prolonged PT and PTT, low fibrinogen, positive D dimer or positive FDP

DIC

3

Prolonged PT, normal PTT

Liver disease, Coumadin therapy, factor deficiency (factor VII OR V, maybe X)

4

Prolonged PTT, normal PT, corrected with mixing studies

Factor deficiency ( VIII, IX X XI or fibrinogen)

5

Prolonged thrombin time

Afribrinogenemia or dysfibrinogenemia or DIC

6

Bleeding into joints (hemarthrosis)

Hemophilia a or B

7

Petechiae, purpura, or eccyhymoses

Low platelets or abnormal platelets

8

Bleeding from gums

Low platelets

9

Primary hemostasis

Platelets

10

Secondary hemostasis

Coagulation cascade

11

Prolonged PT

Factors V, VII, or X, fribrinogen or prothrombin (II), or Coumadin therapy

12

Prolonged PTT

Factors VIII, IX, XI, X or heparin therapy

13

Prolonged bleeding time, normal platelet count

Von Willebrand's disease

14

Prolonged bleeding time, low platelet count

Idiopathic thrombocytopenic purpura (ITP), TTP, or chemotherapy

15

Prolonged PT, PTT, low fibrinogen

DIC

16

Positive D dimer

DIC, deep vein thrombosis, pulmonary embolism

17

Mixing studies, PT or PTT not corrected

Lupus anticoagulant

18

Mixing studies, PT or PTT corrected

Factor deficiency

19

Russell viper venom

Lupus anticoagulant