Coeliac Flashcards
1
Q
Aetiology?
A
Autoimmune condition characterised by intolerance to prolamin protein
2
Q
Pathology?
A
CHAV
Crypt Hyperplasia
Atrophy of Villi
Inflammatory Infitrate
3
Q
what is the genetic linkage to coeliac disease?
A
HLA
4
Q
Symptoms?
A
symptoms of malabsorption:
- abdo pain/cramping
- bloating
- steatorrhoea / diarrhoea
- flatulence
systemic symptoms:
- weight loss
- lethargy
5
Q
Investigation?
A
- serology
- anti-endemysial IgA
- anti-tissue transglutaminase
- endoscopy + biopsy
6
Q
Treatment?
A
withdraw gluten
