COM 1 Cytology week 5 Flashcards
(68 cards)
What does the retina develop from
Optic cup
Name the 2 layers of the retina
-Outer pigmented layer
-Inner Neural layer
Explain the sructure of the retina pigmented layer of the retina:
-What cells it made out of
-What it contains
- Made of cuboidal pr columnar cells
-It contains , gap junctions, secondary lysosomes, peroxisomes smooth ER , phagocytic vacuoles
What are the functions of the retina pigmented layer ( outer layer)
- Absorb light
-Froms blood retina barrier
-Involved in phagocytosis
-Secretes ATP, growth factors
What is the structure of the Neural retina layer
- Contains nine distinct layers, including neuronal and glial cells
What does the Outer nuclear layer of the neural retina contain
- Photoreceptor cell bodies
What does the Inner nuclear layer of the neural retina layer contains
- Contains the nuclei of bipolar, amacrine and horizontal cells
What does the Ganglionic layer of the neural retina contain
- Ganglion cells
Between the first 3 layers of the neural retina Name the 2 plexiform layers
- Outer plexiform layer
-Inner plexiform layer
What does the outer plexiform layer in the neural retina layer contain
- Contains axons from photoreceptors and dendrotes
What does the inner plexiform layer in the neural retina contain
- Contains axons and dendrites
What are Muller cells
They are elongated glial cells that support renal function
What are the functions of Muller cells
-Remove waste
-regulate ion/water balance
-help maintain the blood retina barrier
What do Muller cells form
They from the Outer Limiting Layer (OLL) and the Inner Limiting Membrane ( ILM)
Why can conditions like head trauma cause the pigmented epithelium and photoreceptor layer of the retina to seperate ?
+ What does this seperation cause
- As the pigmenetd epithelium and photoreceptor layers are not firmly joined
- They create intervening space
What are the consequences of Retinal Detachment
- Causes the photoreceptor cells to loose access to the metabolic support provided by the pigmented epithelium,
-This leads to the photoreceptors eventually dying
What are rod cells highly sensitive to + what does this allow
Highly sensitive to light. , allowing vision in low light
Explain the structure of rod cells
They are thin and elongated with 2 segments :
-An outer photosensitive segment and an inner segment for biosynthetic activity
What are the discs in rod cells formed by
In-folding of the plasma membrane
What do cone cells produce
- They produce color vision in adequtely bright lights
Which one is more sensitive rods or cones
Cone cells
Explain the difference between the 3dierent types of cones
-They each have different iodospin pigment sensitive to red blue or green avelenghts
How is Partial colour blindness caused
It is inherited due to mutations in the iodopsin genes
What type of partial colour blindness is the most common
Red green colour blindness