Flashcards in Connective Tissue Disorders CIS - McGowan Deck (26)
35 y/o AA female, bipolar disease, joint pain and episodic chest pain. ANA positive w/ speckled pattern. Rash on cheeks.
Why chest pain?
Why bipolar disease?
Psychiatric disorder common in SLE
45 white female, seizures, fatigue, headache, myalgias, arthralgias, LAD. Rash on face worse after being in sun. ANA positive.
Mood/seizure disorder, Photosensitivity
CREST - limited scleroderma
Calcinosis, Raynauds, Esophageal Dismotility, Sclerodactyly, Telangiectasias
Dermatomyositis (check Polymyositis too)
43 Hispanic woman, hematuria, myalgias, arthralgias. Cr = 2.2 on lab work. Anti-dsDNA and Anti-Sm positive.
50, AA female, fatigue and perioral lesions, has had intermittent symptoms for years. PMH of CAD, chronic intermittent abdominal pain, Hashimoto's, seizures. Positive ANA and dsDNA.
Most likely mortality? Or?
What is the abdominal pain?
Look up Behcet's
45 W female, chest pain, history of SLE. Positive phospholipid antibodies. 2D echo shows valve thickening and verrucous valvular lesions. Called what?
Nodules are ___, meaning w/o bacteria
Libman Sacks endocarditis
Signs of sjogrens
Enlarged parotid gland
Dry eyes, dry mouth
B-cell lymphoma (MALT)
Mood disorder, splenomegaly, diffuse LAD, ARF and chest pain that does not improve w/ position. DVT. Proliferative glomerulonephritis. Cotton wool spots.
What is the chest pain?
IF it was affected w/ position?
SLE + Anti-phospholipid antibody syndrome
Beta2GPI, Anti-Cardiolipin, Antiphospholipid
Pleuritis - position doesn't affect it
45 white, joint pains, recently had pyelonephritis. Discharged on hydralazine for BP and Cipro for infection. Developed malar rash on discharge and diffuse joint pains.
25 Hispanic female, SLE, 16 weeks pregnant. Swelling in legs and elevated BP. Fetal echo shows complete heart block in fetus. Serology in mother?
Swelling and high BP?
What is with this?
These antibodies usually show up in what?
Anti-Ro antibody means high risk of fetal issues
45 white female, finger stiffness. Hard white nodules on fingers. Fingers will go blue sometimes. Perioral furrowing w/ red spots on lips and tongue
What else could go with this?
43 female, dyspnea, gets SOA quickly. Hx of GERD, Raynauds, and carpal tunnel. CXR shows mediastinal LAD and honeycombing. Dry crackles on lung exam. Topoisomerase I Ab positive.
Cause of SOB?
Interstitial lung disease
Pulmonary artery hypertension...think what disease?
Limited scleroderma - CREST
30 AA female, dry itchy skin. Coal miner. Fingers and mouth feel tight. Having difficulty eating. White patches on skin and is self conscious. Ends of fingers have sores. Frequent heartburn.
Most likely etiology?
Other possible etiologies? (4)
Silica - Silicosis
Cocaine, HRT, Appetite suppressants, Bleomycin
30 AA male, fatigue, stiffness, malaise. Muscle weakness, arthralgia. Hx of Raynauds and carpal tunnel. Confusion and HTN. Protein, blood, and granular casts in urine. Anti-centromere Ab negative. RNA pol's 1 and 3 Ab positive.
What is the confusion?
Scleroderma Renal Crisis
7 yo female w/ spot on face. Has been there for weeks. Heathy otherwise.