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Flashcards in NMJ Disorders - Sachen Deck (8)
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1

Tensilon test

Edrophonium injection in Myasthenia Gravis testing

2

Treatments for MG

- AChE inhibitors
- Prednisone
- Immunosuppressives
- Plasma exchange / IVIg
- Thymectomy

3

Drugs that can exacerbate or unmask MG

- Neuromuscular blockers
- Anticholinesterase inhibitors
- Steroids
- Thyroid supplements
- BOTOX
- Magnesium salts
- ***Aminoglycosides

4

Lambert-Eaton...cause?

Common association?

Autoimmune attack of pre-synaptic voltage-gated Ca++ channels

Cancer

5

Proximal weakness, loss of DTRs, myalgias, dry mouth. Better w/ exercise

Reflexes in MG?

Lambert-Eaton myasthenic syndrome


Normal in MG

6

Treatment for Lambert-Eaton

Look for malignancy
AChE inhibitors
3,4-Diaminopyridine
Guanidine hydrochloride
- AE = marrow suppression
Immunosuppression

7

Dry sore mouth and throat, blurry vision, diplopia, nausea, vomiting. Hypohydrosis, total external ophthalmoplegia, paralyses

Botulism

8

Botulism - treatment

Monitoring w/ respiratory support and general medical care

Antitoxin (if possible)