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Oral Pathology > Connective Tissue Lesions > Flashcards

Connective Tissue Lesions Flashcards

1
Q

Most common benign tumor of the oral cavity

A

Fibroma

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2
Q

Fibroma also called

A

Irritation fibroma
Traumatic fibroma

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3
Q

Most common site for fibroma

A

Buccal mucosa near the occlusal plane - cheek biting

Labial mucosa
Tongue
Gingiva

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4
Q

Denture induce fibrous hyperplasia of oral mucosa related to the chronic trauma produced by an ill fitting denture

A

Denture fissuratum
Denture epulis

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5
Q

Common site for denture epulis

A

Facial aspect of alveolar ridge

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6
Q

Difference between peripheral fibroma and fibroma

A

Fibroma is seen in buccal mucosa and tongue commonly

Peripheral is commonly seen on gingiva

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7
Q

Reactive gingival growth identical to peripheral fibroma but contains calcified islands within the fibrous tissue

A

Peripheral ossifying fibroma

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8
Q

Firm slow growing sessile gingival mass covered by normal appearing mucosa commonly found on the facial gingiva of mandible containing stands of ODONTOGENIC epi within the CT

A

Peripheral odontogenic fibroma

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9
Q

Drugs contributing in gingival hyperplasia

A

Phenytoin
Cyclosporin
Nifedipine
Diltiazem
Amlodipine
Verapamil

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10
Q

Benign vascular smooth muscle tumor

A

Leiomyoma

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11
Q

Intraoral sites for leiomyoma

A

Lips
Tongue
Palate
Cheek

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12
Q

Malignant neoplasm of smooth muscle, presents as enlarging ulcerated mass that may or may not be painful intraorally

A

Leiomyosarcoma

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13
Q

Granular cell tumor also known as

A

Granular cell myoblastoma

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14
Q

Intraoral site for granular cell tumor/myoblastoma

A

Dorsal surface of the tongue
Buccal mucosa

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15
Q

Age predilection in granular cell tumor

A

Female
4th to 6th decade of life

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16
Q

Granular cell tumor may be mistaken for SCC because

A

Pseudo epitheliumatous hyperplasia of the overlying oral epi specially on the tongue

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17
Q

Soft tissue tumor in on the max alveolar ridge of newborn females

A

Congenital epulis of newborn

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18
Q

Autoimmune disease involving deposition of large amounts of dense collagen 1 and 3

A

Systemic sclerosis
Scleroderma

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19
Q

Features of scleroderma

A

Females
30-50 yrs of age
2 forms
Limited - no internal organs involved
Diffuse - skin along with heart kidney BB joints etc involved
Pulmonary fibrosis - Leading to pulmonary hypertension and HF

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20
Q

Smooth mask like face, fibrosis of fingers claw like fingers
Atrophic nasal alae
Pinched app giving MOUSE FACE LOOKS

A

Scleroderma
Systemic sclerosis

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21
Q

Oral manifestations of systemic sclerosis

A

Microstomia
Trismus
Purse string app
Dysphagia
Xerostomia
Firm hypomobile tongue
Loss of attached gingiva
Recession
Diffuse widening of PDL
Mand resorption

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22
Q

Generalised widening of PDL
Bilateral resorption of Condyles

A

Systemic sclerosis

23
Q

Common intraoral site for lipoma

A

Buccal mucosa
Buccal vestibule
Tongue
Floor of the mouth

24
Q

Traumatic neuroma

A

Reactive proliferation after nerve damage
Trauma to peripheral nerve

25
Q

Smooth surface non ulcerated nodules usually seen in the mental foramen area
Tongue
Lower lip with a history of trauma (extraction) followed by tenderness with digital pressure

A

Traumatic neuroma

26
Q

Benign neoplasm derived from a proliferation of SCHWANN cells of nerve sheath

A

Schwannoma (neurilemmoma)

27
Q

Features of schwannoma

A

Found in young adults
Common site dorsal surface of tongue
Slow growing encapsulated asymptomatic submucosal mass
Pushes the nerve aside

28
Q

Microscopic patterns of schwannoma

A

Antoni A - spindle cells organised in palisaded pattern around acellular eosinophillic zones called VEROCAY BODIES

Antoni B: spindle cells haphazardly distributed in a delicate fibrillar microcytic matrix

29
Q

Most common benign peripheral nerve neoplasm

A

Neurofibroma

30
Q

Neurofibroma originates from?

A

Schwann cells
Perineural fibroblasts

31
Q

Presentation of neurofibroma

A

Solitary lesions

Multiple lesions in neurofibromatosis type 1

32
Q

Neurofibromatosis 1 also knows as

A

Von recklinghausen’s disease of skin

33
Q

Features of solitary neurofibroma

A

Common in young adults
Slow growing painless soft lesions
Small nodules to large mass
Tongue and buccal mucosa

34
Q

Features of neurofibromatosis type 1

A

Inherited autosomal dominant associated with multiple neurofibromas of the OC and skin
Cafe au lait spots
Iris freckling - lisch nodules
Axillary freckling

35
Q

Crowe sign
Lisch nodules present in

A

Neurofibromatosis type 1
Von recklinghausens disease of skin

36
Q

Which gene is involved in neurofibromatosis type 1

A

NF1 gene

37
Q

Most common type if neurofibromatosis

A

Vin recklinghausens disease of skin - neurofibromatosis type 1

38
Q

Systemic complications of neurofibromatosis type 1

A

Hypertension
Pheochromocytoma
CNS tumors
Mental deficiency
Seizures

39
Q

intraoral manifestations involved in von recklinghausens disease of skin

A

Enlargement of fungiform papillae
Resulting in tongue enlargement

Unilocular or multilocular radiolucencies

Enlargement of mand foramen, mand canal

Increased bone density

Increased coronoid notch dimension

40
Q

Neurofibromatosis type 1 may be associated with

A

Malignant transformation- neurofibrosarcoma
Or
Malignant schwannoma

41
Q

Rare inherited disorder characterized by tumkrs or hyperplasia of neuroendocrine tissues

A

Multiple endocrine neoplasia MEN syndrome

42
Q

Types MEN syndrome

A

MEN 1: tumor hyperplasia of pulmonary gland, parathyroid gland, pancrease and adrenal cortex

MEN 2: subtype 2A sipple syndrome - parathyroid hyperplasia or adenoma
Medillary CA of thyroid, pheochromocytoma of the adrenal medulla
Pancreas not involved

MEN 3: subtype men 2B-

43
Q

Which type of MEN has oral manifestation

A

MEN 3

44
Q

Oral manifestations of MEN type 3

A

Mucucutaneous neuromas
Oral mucosal neuromas - asymptomatic nodules on the lips, ant tongue, buccal mucosa, gingiva and palate

45
Q

Patient presented with multiple asymptomatic nodules in lips and tongue

A

oral mucosal neuromas in MEN 3

46
Q

What is the significance of removing thyroid gland as a prophylactic treatment in MEN 3

A

High risk of medullary carcinoma of the thyroid

47
Q

Benign hamartomas of the lymphatic vessels develops on the skin and MM

A

Lymphangioma

48
Q

Intraoral site for lymphangioma

A

Ant 2/3rd of the tongue resulting in macroglossia
Presents as soft fluctuant nodules or vesicles with pebbly surface ranging in colour from pink to blue

49
Q

Types of lymphangioma

A

Macrocytic : cyst like spaces 2cm or more in diameter - CYSTIC HYGROMA - In the neck involving vital structures

Microcytic: vascular channels of less than 2cm in diameter

MIXED: combi of macro and micro

50
Q

Which type of lymphangioma is common in oral cavity

A

MICROCYSTIC

51
Q

Benign reactive proliferation of the superficial fascia - fibroblasts in young adults presents as rapidly growing firm mass pain and tenderness

A

Nodular fascitis

52
Q

Common intraoral site for nodular fascitis

A

Buccal mucosa

53
Q

Group of locally aggressive fibrous proliferation that show infiltrative destructive and recurrent growth but no tendency to metastasize

A

Fibromatosis

54
Q

Common intraoral site for fibromatosis

A

Paramandibular soft tissues Of children and young adults

Oral Pathology (16 decks)

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