Contraceptives Flashcards Preview

General Pharmacology > Contraceptives > Flashcards

Flashcards in Contraceptives Deck (27):
1

What are estrogen only drugs? (3)

estradiol

estriol

estrone

2

How do estrogen birth control pills work? (3)

reduce bone resorption

metabolic effect

pro-coagulatory

3

What are the side effects of estrogen bc pills? (5)

fluid retention

tender breast

GI issue

migraine

endometrial cancer HRT

4

How does progestin affect fertility? (2)

implantation

corpeus luteum

5

Progesterone decreases fertility by: (2)

affecting basal body temp

endometrial and cervical secretions

6

What are the side effects of progestin only pills? (2)

breakthrough bleeding

mild depression

7

What are progestin only pills? (4)

minipill (norethindrone)

Depo-provera (medroxy)

Mirena (levono)

Implanon (etonogestrel)

8

How are these progestin alone pills delivered? 

Minipill

Depo-provera

Mirena

Implanon

oral daily

IM every 3 months

IUD for 5 years

implant under arm for 3 years

9

What are the estrogen/progestin combo pills? (6)

seasonale

lunelle

nuva ring

ortho evra

lybrel

yaz

10

What combo pill:

levon/estradiol
E/P: 1-84
period 1-4 times per year

Seasonale

11

What combo pill:

estradiol/medroxy
injection every 28-33 days

Lunelle

12

How long does the Nuvaring stay in?

3 weeks

13

What combo BC:

estradiol/norelgestromin
patch ffor 7 days
3 weeks on/1 off
good only for <200 lb. women

Ortho Evra

14

What combo BC:

coninuous levon/estradiol
NO period
increased risk of unrecognized pregnancy

Lybrel

15

What combo BC:

synthetic progestin
drosprenone/estradiol

Yaz

16

What combo BC:

can cause hyperkalemia
lead to fatal heart problems

YAZ

17

What combo BC has most adverse side effects like:

DVT
embolism
stroke
MI
death
gall bladder injury

YAZ

18

Why do we use progestin alone BC?

when estrogen is contraindicated

19

What are post-coital drugs that are not effective if already pregnant?

Plan B (levono)

Preven (levono/estradiol)

20

What is the fertility drug?

clomiphene

21

How does clomiphene (fertility drug) work? 

estrogen receptor antagonist to induce ovulation

22

What is the abortion drug?

mifepristone

23

How does mifepristone work?

antagonist of progesterone and glucocorticoid receptors

24

What are selective estrogen receptor modulators (SERMs) which mimic the effects of estrogen in some organs but act as antagonists in others? (2)

tamoxifen

raloxifene

25

What SERM is estrogen antagonist in breast tissue and inhibits proliferation of breast cancer?

tamoxifen

26

What SERM is an estrogen antagonist in breast and uterine agonist in bone good for osteoporosis?

raloxifene

Also decreases risk of invasive breast cancer.

27

What drug is anti cancer based on inhibition of estrogen synthesis and is first line drug for breast cancer?

femara