CORD/ ALL THAT Flashcards

1
Q

duringweek 4-8 the amnion envelopes to make

A

body stalk + ductus omphalo-entericus + umbilical coelom

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2
Q

ultimately the cord forms from fusion between

A

the two extra-embryonic mesoderm layers

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3
Q

The cord is covered with amnion and the interior contains

A

wartons jelly

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4
Q

what does wartons jelly do

A

Protects the umbilical vessels from possible mechanical pressure and creasing.

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5
Q

very long cord associated with (4)

A

Asphyxia
Death due to knots
Multiple loops of nuchal cord
Cord prolapse

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6
Q

Short cord associated with (2)

A

aneuploidy, and extreme IUGR.

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7
Q

Umbilical coiling is defined as

A

distance between the same umbilical artery making one turn around the umbilical vein.

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8
Q

does umbilical coiling vary with amount of wartons jelly

A

no

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9
Q

Lower degrees of coiling are associated with

A

lesser degrees of fetal growth

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10
Q

In the 2nd & 3rd trimesters, the largest contributor to the size of umbilical cord is associated with

A

wartons jelly

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11
Q

In the 2nd and 3rd trimester thin cord can be seen in

A

IUGR

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12
Q

In the 2nd and 3rd trimester thicker cord can be seen in (5)

A
Aneuploidy
Diabetes,
Fetal macrosomia,
Placental abruption, 
Rhesus isoimmunization
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13
Q

Rhesus Isoimmunization occurs when

A

mother is Rh-negative and the baby is Rh-positive, the mother produces antibodies (including IgG) against the Rhesus D antigen on her baby’s RBCs.
regarded as insufficient immune tolerance in pregnancy

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14
Q

does Rhesus disease get better with more births

A

no becomes worse with each additional Rh incompatible pregnancy.

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15
Q

2 benign tumors of umbilical cord

A

hemangioma and teratoma

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16
Q

hemangiomas occur at what end of the cord

A

placental end

17
Q

appearance of hemangiomas

A

Multicystic appearance

may be impossible to differentiate from a teratoma, hematoma or umbilical cord cyst.

18
Q

hemangioma associated with

A

still birth

19
Q

hemangiomas might be result of

A

large pseudocysts

20
Q

hemagioma aka

A

angiomyxomas

21
Q

teratoma appearance

A

solid with or without cystic areas

22
Q

teratoma contains what tissue

A

tissue from all three germ cell types

23
Q

absent coiling occurs in __% of the cases

A

5%

24
Q

absent coiling associated with

A
single umbilical artery
both marginal and velamentous umbilical cord insertions
multiple gestations
aneuploidy
preterm delivery 
fetal demise
25
Q

some true knots of cord associated with (2)

A

fetal death or just normal variants

26
Q

where are umbilical cysts most frequently seen

A

portions closest to the fetus

27
Q

where does umbilical cyst develop from? (2)

A

allantois and omphalomesenteric duct

28
Q

Pseudo-cysts may develop through _____ giving cord a _______ appearance

A

through liquefaction of Wharton’s Jelly giving the umbilical cord a hydropic appearance.

29
Q

when are cysts normal

A

1st trimester

30
Q

if cysts persist in 2nd and 3rd they suggest

A

chromosomal and/or structural abnormalities

31
Q

when is nuchal cord often seen

A

2nd or 3rd trimester

32
Q

cause of single umbilical artery (SUA)

A

congenital

33
Q

absence of the left or right umbilical artery is much more common

A

left

34
Q

single umbilical artery (SUA) more common in

A

twins

35
Q

4 associations of single umbilical artery (SUA)

A

Intra-uterine growth restriction (IUGR)
Aneuploidy
Renal abnormalities
Cardiac abnormalities