CORD/ ALL THAT Flashcards

1
Q

duringweek 4-8 the amnion envelopes to make

A

body stalk + ductus omphalo-entericus + umbilical coelom

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2
Q

ultimately the cord forms from fusion between

A

the two extra-embryonic mesoderm layers

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3
Q

The cord is covered with amnion and the interior contains

A

wartons jelly

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4
Q

what does wartons jelly do

A

Protects the umbilical vessels from possible mechanical pressure and creasing.

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5
Q

very long cord associated with (4)

A

Asphyxia
Death due to knots
Multiple loops of nuchal cord
Cord prolapse

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6
Q

Short cord associated with (2)

A

aneuploidy, and extreme IUGR.

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7
Q

Umbilical coiling is defined as

A

distance between the same umbilical artery making one turn around the umbilical vein.

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8
Q

does umbilical coiling vary with amount of wartons jelly

A

no

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9
Q

Lower degrees of coiling are associated with

A

lesser degrees of fetal growth

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10
Q

In the 2nd & 3rd trimesters, the largest contributor to the size of umbilical cord is associated with

A

wartons jelly

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11
Q

In the 2nd and 3rd trimester thin cord can be seen in

A

IUGR

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12
Q

In the 2nd and 3rd trimester thicker cord can be seen in (5)

A
Aneuploidy
Diabetes,
Fetal macrosomia,
Placental abruption, 
Rhesus isoimmunization
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13
Q

Rhesus Isoimmunization occurs when

A

mother is Rh-negative and the baby is Rh-positive, the mother produces antibodies (including IgG) against the Rhesus D antigen on her baby’s RBCs.
regarded as insufficient immune tolerance in pregnancy

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14
Q

does Rhesus disease get better with more births

A

no becomes worse with each additional Rh incompatible pregnancy.

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15
Q

2 benign tumors of umbilical cord

A

hemangioma and teratoma

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16
Q

hemangiomas occur at what end of the cord

A

placental end

17
Q

appearance of hemangiomas

A

Multicystic appearance

may be impossible to differentiate from a teratoma, hematoma or umbilical cord cyst.

18
Q

hemangioma associated with

A

still birth

19
Q

hemangiomas might be result of

A

large pseudocysts

20
Q

hemagioma aka

A

angiomyxomas

21
Q

teratoma appearance

A

solid with or without cystic areas

22
Q

teratoma contains what tissue

A

tissue from all three germ cell types

23
Q

absent coiling occurs in __% of the cases

24
Q

absent coiling associated with

A
single umbilical artery
both marginal and velamentous umbilical cord insertions
multiple gestations
aneuploidy
preterm delivery 
fetal demise
25
some true knots of cord associated with (2)
fetal death or just normal variants
26
where are umbilical cysts most frequently seen
portions closest to the fetus
27
where does umbilical cyst develop from? (2)
allantois and omphalomesenteric duct
28
Pseudo-cysts may develop through _____ giving cord a _______ appearance
through liquefaction of Wharton’s Jelly giving the umbilical cord a hydropic appearance.
29
when are cysts normal
1st trimester
30
if cysts persist in 2nd and 3rd they suggest
chromosomal and/or structural abnormalities
31
when is nuchal cord often seen
2nd or 3rd trimester
32
cause of single umbilical artery (SUA)
congenital
33
absence of the left or right umbilical artery is much more common
left
34
single umbilical artery (SUA) more common in
twins
35
4 associations of single umbilical artery (SUA)
Intra-uterine growth restriction (IUGR) Aneuploidy Renal abnormalities Cardiac abnormalities