CV6 Flashcards

1
Q

is vascular smooth muscle always in a state of contraction

A

yes

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1
Q

where is the smooth muscle layer in a vascular smooth muscle

A

media (the middle one)

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2
Q

what make up the microcirculation

A

arterioles, capillaries, and venules

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3
Q

what is a metarteriole?

why isn’t it an arteriole

A

act as a bypass channel

not quite an arteriole because its not fully vascular smooth muscle

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4
Q

what are precapillary sphincters

A

vascular smooth muscle at the junctions between the arterioles and capillaries

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5
Q

what are the walls of arteries like

A

stiff and springy

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6
Q

are metarterioles thicker or thinner than capillaries

A

thicker

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7
Q

gases can normally ___________ across the endothelial cells

A

passively diffuse

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8
Q

what are capillaries linked by

A

interendothelial junctions

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9
Q

what are fenestrations? where are they located

A

pores along the membrane that allow transport

cells

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10
Q

what are capillaries usually surrounded by

A

pericytes (like a blood brain barrier)

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11
Q

what is the most common capillary

A

continuous capillary

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12
Q

which capillary does not contain fenestrations

A

continuous

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13
Q

which capillary has the least amount of transport and exchange

A

continuous

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14
Q

which capillaries have fenestrations

A

fenestrated and discontinued

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15
Q

which capillaries have a thin diaphragm making them selective

A

fenestration capillaries

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16
Q

which capillaries are found in the liver and spleen

A

discontinuous (sinusoidal)

17
Q

what are the three methods of transport in capillaries

A

transcellular transport
paracellular transport
transcytosis

18
Q

what is transcellular transport in capillaries

A

diffusion across the endothelial cell membrane
(aquaporin channels)

19
Q

what is paracellular transport in capillaries

A

diffusion through inter endothelial junctions, pores, or fenestration

20
Q

what is transcytosis In capillaries

A

endocytosis, vesicular transport, etc

21
Q

are there more veins or arteries

A

more veins. that is why they are the volume reservoir

22
Q

do arteries or veins have a thinner layer of vascular smooth muscle and elastic tissue

23
Q

what is angiogenesis

A

the formation of new blood vessels

24
is adult microcirculation constant
yes
25
what is a major driver of blood vessel growth
vascular endothelial growth factor
26
what circuit is blood pressure related to
systemic circuit
27
why are arteries the pressure reservoirs
they ensure that blood continues to flow even during ventricular relaxation there is a pressure gradient at all times because they store pressure in elastic walls
28
when is aortic pressure highest
ventricular contraction (systole)
29
how to calculate pulse pressure
pulse pressure = systolic pressure - diastolic pressure
30
where does pulse pressure usually exist
the arterial/arteriole side of the circuit
31
can a pressure wave be felt
yes
32
what is the mean arterial blood pressure
reflects the driving pressure for blood flow (commonly measured in bicep as a reflection of ventricle driving pressure
33
mean arterial blood pressure calculation
map = Diastolic + 1/3 (systolic - diastolic)
34
is the MAP an average of systolic and diastolic pressures? why or why not
no, because the time spent in systole is shorter than the time spent in diastolic
35
what is hypotension
when the blood pressure is chronically toon low (lower than 90/60)
36
what is hypertension
when the blood pressure is chronically higher (over 140/90)
37
what is a blood leak in the brain called ? what is it caused by
cerebral hemorrhage could be because of hypertension leading to weakened vessel walls
38
what is blood pressure estimated by
sphygmomanometer
39
what is a Karotkoff sound? what is it caused by
it is the audible sound of whooshing of blood it is caused by pulsatile blood flow through the compressed artery