DD Benign neoplasms of skin Flashcards Preview

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Flashcards in DD Benign neoplasms of skin Deck (18):
1

Infantile Hemangioma

aka Capillary or Strawberry Hemangioma

○ Most common soft tissue tumor of infancy (10-12%); benign endothelial cell neoplasm

2

Systemic complications of infantile hemangioma

There are a lot, one of the bad ones:

Kasabach-Merritt syndrome (a consumptive thrombocytopenic coagulopathy) and

high output congestive heart failure.

3

Port Wine Stain typically follows what distribution?

trigeminal nerve

4

Skin tags

acrochordons
- 1/4 of adults have at least 1 - gross

5

Positive dimple "Fitzpatrick" sign
indicates what?

pinch lesion and should see slight downward movement of tumor

Dermatofibroma

6

Barnacles of Life

Seborrheic keratosis
Benign tumor of the hair follicle, distributed mainly in on the head, neck, trunk.

slightly raised, light brown to black papules or plaques.

7

melanocyte nests (nevus cells) exclusively within the ____________

dermis. (moles are intradermal)

8

Blue Nevus
how does it occur?

§ Dermal proliferation; produce lots of melanin

- Due to Tyndall Effect, blue color is reflected back (shorter wavelengths)

9

Endothelial Cell benign skin growth

○ Cherry Angiomas
○ Infantile Hemangioma: embolized placental cells or angioblasts that differentiate toward placental type.
○ Port Wine Stain

10

The Sebaceous gland is the cell type of origin for which benign skin growths?

Sebaceous Hyperplasia and Nevus sebaceous

11

The Fibroblast is the cell type of origin for which benign skin growths?

Dermatofibroma

12

Keratinocytes are the cell type of origin for which benign skin growths?

Seborrheic keratosis

13

Melanocytes benign skin growth

nevi, melanoma,
ephelides (freckles),
lentigo (sunspots),
café au lait macule

14

Dermatofibroma malignant potential if:

if presented as large and enlarging lesion, aka dermatofibrosarcoma protuberans (DFSP)

15

Seborrheic keratoses malignant potential if:

aka Sign of Leser Trelat, which is associated with adenocarcinoma of the stomach in 60%.

16

Congenital Nevi malignant potential if:

if >10 cm; can occur in 1:20,000 newborns, or if >20cm in older patients, 1% will have risk of malignancy. If malignant, 50% appeared in first three years.

17

Dysplastic Nevi malignant potential if:

Increased risk for development of melanoma if pt had family history of multiple dysplastic nevi melanoma

18

Recognize the fact that port wine stains are congenital vascular malformations.
- what is it?
- how does it present?
- complications?

• Vascular malformation that is presented at birth and persists into adulthood; typically due to somatic mutation in GNAQ.
○ Presented as an overgrowth of an extremity covered by a large port wine stain.
○Complications can include varicose veins, venous stasis, edema, and ulceration.