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Flashcards in DD Topical Therapeutics in Derm Deck (18):
1

Vehicle in dermatology

the substance in which the active ingredient is sitting in/delivered in

2

What type of application/vehicle causes less allergy/sensitization?

Ointment

3

Ointments

Water in oil emulsion

4

Creams

Oil in water emulsion

5

Gels

Semisolid emulsion in alcohol base

6

Lotions/Solutions

Powder in water

7

Foams

Pressurized collections of gaseous bubbles in a matrix of liquid film

8

Potency of:
Ointments
Creams
Gels
Lotions/solns

Ointments - strong
Creams - moderate
Gels - strong
Lotions/solns - low

9

1 gram of cream covers ________

1 gram of cream covers a 10cm x 10cm area of skin

-The rule of 10s

10

1 gram of ointment goes ____ further than 1 gram of cream.

10%

-The rule of 10s

11

FTU

• 1 FTU = 0.5 g

covers palm and back of hand.

or two palms

12

Hydrocortisone

2.5%
"The Gentle Touch"
• Class 7, lowest potency
• Mild eczema in children
• Good for face, intertriginous areas or groin

13

Hydrocortisone adverse effects

• Skin atrophy with long-term use

• Telangiectasia:

• Striae formation: (stretch marks)

14

Triamcinolone Acetonide

0.1% cream or ointment"The Almost All-Purpose Weapon"
• Class 4 - mid potency
• Available in many many sizes
• Effective against moderate spongiotic dermatoses
• Eczematous dermatitis, atopic dermatitis, allergic contact dermatitis, arthropod bites, id reactions, drug reactions
• Good for trunk and extremities

15

Triamcinolone Acetonide adverse effects

• Long-term use is bad for facial, intertriginous and groin areas
• Leads to atrophy
• Steroid-induced rosacea

16

active ingredient in ointment in cream or ointment delivers it stronger?

ointment

17

Clobetasol Propionate

0.05% cream or ointment"Hercules"
• Class 1, super potent steroid
• Best in acute eruptions
• Contact dermatitis
• Acute drug eruptions

18

Clobetasol Propionate adverse rxns

• Avoid the face, intertriginous areas, and groin because skin is thin.
• Leads to atrophy
• Steroid-induced rosacea
• Adrenal suppression
• Cushing's syndrome
• Growth retardation
• NO MORE THAN 50g per week!