DD Cutaneous Infxns and Infestations Flashcards Preview

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Flashcards in DD Cutaneous Infxns and Infestations Deck (12):
1

Anti-microbial peptides:

Alpha-defensins (hNP1, hNP2),
beta-defensins (hBD-1,-2,-3)
Cathelicidin (hCAP-18)
Psoriasin and RNase7

2

What smear do you use to dx HSV and VZV?

Tzanck preparation (smear - look for multinucelated keratinocytes and large vesicular nuclei in keratinocytes),

3

Honey-colored crust
dx?

Non bullous impetigo most likely caused by
strep since it is non bullous (maybe staph)

- If bullous impetigo then suspect Staph aureus (scalded skin)

4

Who is at increased susceptibility of getting cellulitis?

very young, old, immunocompromised, IV drug users, pts w/chronic ulcers.

5

Cliff drop border

St. Anthony's fire
--> Erysipelas

6

Cellulitis

primary lesion is tender, illdefined area, erthematous, painful, variable lymphadenopathy, streaking.

7

Hunterian Chancre

Papule breaks down to ulcer -->
Non- tender ulcer
Indurated (hardening)
Heals 3-6 weeks
Lymphadenopathy

- Dx syphilis

8

KOH exam to look for what?

Hyphae of arthrospores

indicating fungal infxn - ie dermatophyte, candidiasis

9

Food source of Tinea Versicolor

follicular lipids

10

Tinea (Pityriasis) Versicolor show as hypopigmented patches bc?

production of azelaic acid that inhibits function of tyrosine produced by melanocytes.

11

Scabies life cycle

30 day lifecycle w/ female laying down 60 to 90 eggs that mature in approximately 10 days.

12

Scabies vs lice?

You cant see scabies: look for nodules/burrows or use microscope

Lice: tan-brown, 6 legs