Dermatology Flashcards
(187 cards)
1
Q
Acne Vulgaris in pregnancy :
A
Oral Erythromycin
Erythro-MOM-mycin—mom—safe in pregnancy
2
Q
Potency of steroids :
A
Colombo Children—Cmb Ch
Clobetasol—Soul-Potent.
M
B—Betamethasone
C—Colbetasone
H—Hydrocortisone
3
Q
K/c/o Atopic eczema—on Hydrocortisone. Which drug to give next ?
A
Give colbebetasone.
Colombo Children—Cmb Ch
Clobetasol—Soul-Potent.
M
B—Betamethasone
C—Colbetasone
H—Hydrocortisone
4
Q
Blistering itchy rash around umbilicus + 2/3rd trimester.
A
Pemphigoid gestations
5
Q
Prurtic lesion around Abdominal Striae + last trimester. Dx?
A
Polymorphic Eruption of Pregnancy
6
Q
Most important prognostic factor for Melanoma :
A
Invasion Depth of the tumour
7
Q
Eczema Herpeticum, which viruses are involved ?
A
HSV 1
HSV 2
Coxsackie Virus
8
Q
Apart from HSV1 and HSV 2 , which virus is involved in eczema herpeticum ?
A
Coxsackie virus
9
Q
Which other dermat condition is ass with eczema herpeticum ?
A
Atopic Dermatitis
10
Q
K/C/O Atopic eczema + erythematous vesicles with some lesions eroded + Face—extensor surface—palms and soles—oral ulcers. Dx?
A
Eczema Herpeticum
11
Q
Purple non blanching + Reticular rash—net like pattern across limbs and torso
A
Livedo reticularis
12
Q
Livedo reticularis is ass with which Rheumat condition ?
A
SLE
13
Q
Most specific antibody in SLE :
A
Anti Smith antibodies
SMecific antibody—Anti SMith
14
Q
Gold standard diagnostic test for Dermatitis herpitformis :
A
Skin Biopsy—To look for deposition of IgA in Dermis.
15
Q
Which dermatology condition is ass with coeliacs ?
A
Dermatitis herpetiformis
16
Q
Which Ig in Dermatitis Herpetiformis ?
A
IgA
17
Q
on which surface is dermatitis herpetiformis ?
A
On extensor surface.
18
Q
K/C/O coeliacs + Itensly itchy vesicular skin lesion + extensor surfaces—elbows, buttocks , knees. Dx?
A
Dermatitis Herpetiformis
Ix—Skin Biopsy to look for deposition of IgA in dermis
19
Q
Melanoma + Red or Black lump on face which bleeds. Dx ?
A
Nodular Melanoma
20
Q
Most aggressive and early metastasis form of Melanoma.
A
Nodular Melanoma
21
Q
Light brown thickened patch of skins in axillae and palms + Small finger like projections from lips + pruritis + extensive lesion involving palms and soles and mucosa.
Underlying diagnosis and Ix ?
A
Acanthosis Nigricans secondary-to Gastric Cancer.
Ix—Gastroduodenoscopy.
22
Q
Lesion on lower lip. Dx and Rx for minimal scarring.
A
Squamous Cell Carcinoma.
Rx for minimal scarring: MOHS Micrographic Surgery.
23
Q
Shiny erythematous plaque with silvery surface on flexure aspect—Armpits, groins, calves + Auspitz sign positive. Dx and Rx:
A
Flexural Psoriasis
Rx— First line —Topical Steroids—
24
Q
First line Rx in Flexural Psoriasis :
A
Topical Steroids
25
Trichophyton Rubrum nail infection Rx:
Oral Terbinafine for 12 weeks
26
is hypertension a side effect of retinoids ?
No
Intracranial Hypertension is a side effect of retinoids
27
seborrhoeic dermatitis Common association :
HIV
Parkinson’s
28
Nivolumab associated colitis Rx :
Oral prednisolone
29
Pityriasis Versicolor is ass with which HHV ?
Ass with HHV 8 ( Herpes Hominis Virus )
30
HHV 7(Herpes Hominis ) is associated with :
Pitryriasis roseaola
7 Homies proposed with a ROSE to Namita.
31
Pitryriasis Roseola is associated with which Herpes ?
HHV 7.
7 Homies proposed with a ROSE to Namita.
32
HHV 7 is :
Herpes Hominis
7 Homies proposed with a ROSE to Namita.
33
H/o URTI —-Herald Patch on Trunk—Erythematous oval scaly patches
Pitryriasis Roseola
34
Pitryriasis Roseola
H/o URTI —-Herald Patch on Trunk—Erythematous oval scaly patches
35
K/C/O Lung cancer + small erythematous annular patch, slowly enlarging into polycyclic patches with a wood-grain appearance
Erythema Gyratum Repens
36
Nivolumab + Scaly Red Plaque on extensor surface. Dx?
Topical Betamethasone
37
Alopecia Areata Rx
Topical Steroids
38
Keratocanthoma Rx?
Urgent Referral to Dermatology for Urgent Excision.
39
Volcano like spot on left cheek :
Keratocanthoma
40
Keloid scars - more common in
Young black males
41
Psoriasis on extensors first line
Psoriasis on flexure aspect :
Topical steroids plus vitamin D analogue
Topical steroids
42
Not a recognised cause of Eryhroderma :
Lichen Planus
43
Lupus Pernio is ass with ?
Sarcoidosis
44
TB ass skin conditions :
Lupus Vulgaris
Scrofuloderma
verrucosa Cutis
Erythema Nodosum
45
Painful Multiple circular ulcerated lesions between 1 and 3mm in diameter on the right side of her face, spreading from the ear to the chin and neck. Her hearing is unaffected.
Eczema Herpeticum
46
Mucosal Involvement in Steven Johnson Syndrome ?
Prominent
47
Nikolsky sign in Steven Johnson ?
Positive.
48
K/C/O HIV—Fever Myalgia—Flaccid Blistering and Rash in Torso and Oral Mucosa + Nikolsky-Positive
Steve Johnson Syndrome
49
Non Healing Painless Ulcer ass with a chronic scar on leg. Dx?
Squamous Cell Carcinoma
50
Common Complication of seborrhoeic dermatitis:
Otitis External and Blepharitis
51
Skin cancer associated with Transplant :
Squamous Cell Carcinoma
52
Numerous scaly patches are noted on the forehead, as well as greasy, flaky lesions in the nasolabial folds.Dx and Complication
Seborrhoeic dermatitis
Complication- Blepharitis
53
itchy white spots typically seen on the vulva of elderly women
Lichen Sclerosus
54
porphyria cutanea tarda ass with ?
Hepatitis C
55
K/C/O Hepatitis C + onycholysis and a blistering erythematous rash on the dorsal aspect of the hand and face + hyperpigmentation and hypertrichosis on the face
Porphyria Cutanea Tarda.
56
Which chronic condition is ass the most with seborrhoeic dermatitis
HIV
57
Rx for Pyoderma Gangrnosum:
Oral prednisolone
58
On Leg—initially Small Pustule/Red Bump—Skin breaks down—Resulting in painful ulcers with purple violaceous edges. Dx:
Pyoderma Gangrenosum
59
Pyoderma Gangrenosum
On Leg—initially Small Pustule/Red Bump—Skin breaks down—Resulting in painful ulcers with purple violaceous edges
60
Pyoderma Gangrenosum ass features :
IBD
RA
SLE
Leukemias
61
Most common side effect of Isoretinoids :
Dry skin
62
Lichen planus occurs in which aspect ?
Flexure aspect
63
Lichen Planus oral mucosa involvement ?
Oral Mucosal involvement present
64
white lacy pattern in oral mucosa :
Oral Lichen Planus
65
Most common site for keloid scar :
Sternum
66
Scabies Rx:
all skin including scalp + leave for 12 hours + retreat in 7 days
67
Hyperhydrosis first line :
Topical Alluminium Chloride
68
Tonsillitis + Acute onset of tear-drop scaly papules / Lesion less than 1 cm + on trunk and limbs. Dx:
Guttate psoriasis
69
Holiday + She also notes that the skin on her hands is extremely fragile and tears easily + Hypertrichosis
Porphyria Cutanea Tarda
70
Mucosal lesions + Blistering Flaccid lesion.
Pemphigus Vulgaris
71
Mucosal lesion in Bullous Pemphigoid ?
No
72
Mucosal lesion Pemphigus Vulgaris ?
Yes
73
Bullae in Bullous Pemphigoid ?
Tense Bullae or Tense Blisters
74
Bullae in Pemphigus Vulgaris ?
Flaccid
75
Pellagara is due to deficiency of :
B3 ( Pellagara )
76
Rosacea first line :
Topical Ivermectin
77
Rosacea becomes worse with :
Sunlight and Alcohol
78
Rosacea severe papules Rx:
Topical Ivermectin and Oral Doxycycline
79
3rd trimester + Pruritis on lower abdomen and striae
Polymorphic eruption of pregnancy
80
Polymorphic eruption of pregnancy Site :
Abdomen Striae and Lower Abdomen
81
Pompholyx eczema Is aggravated by :
Humidity
High Temperature
82
Intense pruritic erythematous/burning on palmar aspect of hands and soles. Dx?
Pompholyx eczema
83
Pompholyx eczema
Intense pruritic erythematous/burning on palmar aspect of hands and soles
84
H/o Exposure to sunlight + Asymotomatic Tan Brown lesion on temple region on face + since 5 years:
Lentigo Maligna
85
Total Parentral Nutrition can lead to which Mineral deficiency ?
Zinc deficiency
86
TPN/ Alcohol excess + rash around mouth
Zinc deficiency
87
Most common form of malignancy ass wth Acanthosis Nigricans is :
Gastric adenocarcinoma
88
Histology of squamous cell carcinoma :
Keratin Pearls
89
Rash of Eczema Herpeticum
monomorphic punched-out erosions and blisters
90
Eczema Herpeticum ass with :
Eczema
91
Eczema Herpeticum Rx:
IV Acyclovir
92
Most common cancer in lower lip ?
Squamous cell carcinoma
93
Which cells are involved in Steven Johnson Syndrome :
T Cells
Delayed Hypersensitivity Reactoin—Sensor door is buffering(delayed), therefore Tomahawk axe is used to break the door
94
Minocycline side effect:
Irreversible sin pigmentation
95
Role of emolients in Seborrhoeic Dermatitis :
No Role
96
Which drug not to give in Rosacea ?
Steroids
97
Actinic Keratosis Rx:
Topical Flouroracil
98
Elderly + Sun exposure + Red scaly lesion, which now is erythematous and rough to touch + On Sun exposed area—Back of arm + Face + Scalp
Actinic Keratosis
99
two month history of a rapidly growing lesion on his right forearm. The lesion initially appeared as a red papule but in the last two weeks has become a crater filled centrally with yellow/brown materia
Keratocanthoma
100
Tiinea Capitis is caused by :
Trichophyton tonsurans
101
Non Sedating anti histamines :
Loratidine
102
Pemphigoid Vulgaris immunofluorescence of the skin biopsy:
IgG and C3 at dermo epidermal junction
P3mphiGoid—IgG and C3
103
Is Alopecia a feature of Zinc deficiency ?
Yes
104
Is short stature a feature of Zinc Deficiency ?
Yes
105
Is Gingivitis a feature of zinc deficiency ?
No
106
Most associated with onycholysis ?
Raynauds
107
Does phenytoin cause alopecia ?
No
It causes Hirsutism
108
Ciclosporin side effect ?
Hypertrichosis
109
Psoriatic Arthritis Rx:
Etanercept
110
Alcohol + rash around the anus + loss of libido and Impotence. Dx:
Zinc Deficiency
111
Lichen planus first line :
Topical Potent steroids
112
H/o holiday + on trunk—patches may be hypopigmented, pink or brown (hence versicolor) + pruritis
Dx: Pityriasis Versicolor
Malasazia Furfur
Rx: Ketoconazole shampoo
113
systemic mastocytosis Ix?
Urinary Histamine
114
H/o Depression, Anxiety—linear well demarcated skin lesions which appear excoriated + La Belle Indifference —Apathy and Indifference towards lesion.
Dermatitis Artefacta.
115
Dermatitis Artefacta.
H/o Depression, Anxiety—linear well demarcated skin lesions which appear excoriated + La Belle Indifference —Apathy and Indifference towards lesion.
116
Which meds exacerbate Plaque Psoriasis ?
B blockers—Propranolol
117
Malnourished child + acral, periorificial and perianal distribution + Poor cognitive and Growth development
Zinc Deficiency
118
Abdominal pain+ Diarrhoea+ Repeated episodes of flushing + urticarial skin lesions on the trunk.
Systemic Mastocytosis
119
Systemic Mastocytosis
Abdominal pain+ Diarrhoea+ Repeated episodes of flushing + urticarial skin lesions on the trunk.
120
Pyoderma Gangrnosum First line Rx:
Oral Prednisolone
121
Tense Blistering lesion on legs+ No mucosal Involvement
Bullous Pemphigoid
122
Which psych meds can trigger Psoriasis ?
Lithium
123
Diabetes + waxy yellow shin lesions
necrobiosis lipoidica diabeticorum
124
treatment of choice for facial hirsutism
Topical Elfornithine
125
Hyperthyroidism/Graves disease skin manifestation :
Pretibial myxoedema: B/L symmetrical Non Pitting oedema—Orange peel appearance
126
Pretibial myxoedema:
Associated with Hyperthyroidism/graves + B/L symmetrical Non Pitting oedema—Orange peel appearance
127
Pellagara Triad and cause :
cause: B3(Niacin). Triad : dermatitis, diarrhoea and dementia
128
patch of pigmented skin on her toe, which has been slowly enlarging over the past five months+ proximal nail fold affected. Dx?
Acral lentiginous melanoma
129
HIV + extensive pink umbilicated lesions visible on his trunk
Molloscum Contagiosum
130
In adults molloscum contagiousum is associated with :
HIV
131
Is Lupus Vulgaris is associated with Koebner’s ?
No
132
Is molloscum Conatagiousum associated with Koebner’s ?
yes
133
15 year old—scarring acne. Rx?
Retinoids
134
Patients with scabies who complain of pruritus __ weeks following treatment should be retreated
6 weeks
135
Scabies which type of reaction ?
delayed type IV hypersensitivity reaction
136
Is Malathion used in scabies ?
yes
137
Bullous Pemphigoid Rx?
Oral Steroids
138
On Groin and Axillae + well-defined pink/brown patches with fine scaling and superficial fissures.
Erythrasma
139
Impetigo First line Rx?
Topical Fusidic acid
140
Impetigo + Prolonged Hospital Stay + No response to Fusidic acid. Dx and Rx?
Suspect MRSA
Rx: Topical Mupirocin
141
necrolytic migratory erythema Which tumour ?
All Migratory things are pancreatic tumours
This one : Glucagonoma
Body is necrosed because of glucose
142
most likely antibodies directed against in Bullous Pemphigoid :
Hemisdesmosomal BP antigens
143
Apart from legs, where else Pyoderma gangrenosum Can happen ?
Stoma site
144
Hard skin on scalp + white, hyperkeratotic lesion on the crown of his head.
No fungal infection on tests.
Scalp psoriasis
seb derm: dandruff / hairline scaling & erythema. Also will not generally form discrete area - more diffuse.
kerion: zoonotic fungal infection so often more signs of inflammation than typical human fungal infections
145
Erythema multiforme in which sexual infection ?
Herpes simplex virus
146
Which antibiotic is associated with Steven Johnson syndrome ?
Sulphonamides—Co trimoxazole
147
Is Azoospermia associated with Yellow Nail Syndrome ?
No
148
Yellow Nail Syndrome Associations :
Pleural Effusions
Brochiectasis
Chronic Sinus infection
Congenital Lymphoedema
149
K/C/O Hypothryoidism + erythematous rash with patches of hyperpigmentation and telangiectasia is found
Erythema Ab Igne
150
DM related skin conditions:
Necrobiosis lipoidica
Granuloma annualare
Infection—caddiasis, staph
Neuropathic ulcers
Vitiligo
Lipoatrophy
151
Is Sweet’s syndrome associated with with Diabetes ?
No
152
Guttate Psoriasis Rx and Rx to accelarate recovery ?
Rx: Resolves Sponataneously
To accelarate: Ultraviolet B Phototherapy
153
Porphyria Cutana Tarda which enzyme deficiency ?
uroporphyrinogen decarboxylase
154
erythematous yellow scaly rash over his nasolabial fold, upper back and chest.
seborrhoeic dermatitis
155
Does Roacea have itchiness ?
No
156
Does seborhoeic dermatitis have itchiness ?
Yes
157
Differentiating feature between seborhoeic and Rosacae ?
Seborhoeic has itchiness
158
Differentiate carcinoid syndrome from systemic mastocytosis :
Carcinoid syndrome may cause abdominal pain, flushing and diarrhoea. However, a reddish-brown papular rash which is Darier's sign positive is much more characteristic of systemic mastocytosis than carcinoid syndrome.
159
Seborrhoeic dermatitis - first-line treatment:
Topical Ketoconazole
160
Pityriasis is caused by :
Malasazia Furfur
161
Pregnancy + large, flat, symmetrical, brown-pigmented patch across her cheeks, forehead, nose and upper lip.
Melasma
162
Diagnosis for allergic contact dermatitis :
Skin Patch test
163
Which epileptic drugs causes Erythema Multiforme ?
carbamazepine
164
Which two condition most associated with Acanthosis Nigricans ?
Gastric Cancer
Hypothyroidism
165
Psoralen and PUVA therapy can lead to :
Squamous Cell Carcinoma
166
Difference between allergic contact dermatitis and Irritant Contact Dermatitis :
Irritant contact dermatitis : it usually presents with erythema and scaling rather than vesicles
167
Dye + Vesicular rash
Allergic contact dermatitis
168
discrete area of hair loss on the left temporal region with no obvious abnormality of the underlying scalp. What is the most likely diagnosis?
Alopecia Areata
169
Erythema ab igne can lead to :
Squamous Cell Carcinoma
170
Keloid Scar Rx:
Intralesional Triamcinolone
171
Known Thyroid Disorder + Number of patches of 'pale skin'
Vitiligo
172
flesh-coloured or pink lesions with a pearly appearance On Nose :
Basal Cell Carcinoma—Above Upper lips , so Basal Cell Carcinoma
173
Tender Shin Lesions
Erythema Nodosum—common cause—. Sarcoidosis
174
oval, erythematous lesions with a collarette of scale just inside the edge—5-10 cm in size + on trunks
Pityriasis Rosacae
Guttate is 1-10 mm in size
175
Hereditary haemorrhagic telangiectasia Inheritance :
Autosomal Dominant with age related penetrance
176
Toxic Epidermal Necrolysis is caused by which drug ?
Phenytoin
177
Phenytoin + systemically unwell + Positive Nikolsky sign
Toxic Epidermal Necrolysis
178
3-year-old girl is taken to her doctor due to a rash on the right upper arm. On examination multiple raised lesions of about 2 mm in diameter are seen. On close inspection a central dimple is present in the majority of lesions. What is the likely diagnosis?
Molloscum Contagiosum
179
Management of venous ulceration
Compression Bandaging
180
A large, shallow ulcer is visible, superior to the medial malleolus; it does not look infected + High ABPI
Venous ulcer
181
Erythema Nodosum confirmed. Next Ix?
Chest X ray—to look for the cause such as sarcoidosis and TB
182
Erythema Nodosum healing ?
Heals without scarring within 1-2 months
183
Does Amyloidosis cause Erythema Nodosum ?
No
184
Recurrent epistaxis + Melena + Telangiectasia on face. Dx?
Hereditary haemorrhagic telangiectasia
185
Suspected venous ulcer, next investigation ?
ABPI
186
Diabetes + number of 3-4 mm smooth, firm, papules which are hyperpigmented and centrally depressed.
Granuloma annulare
Necrobiosis lipoidica diabeticorum typically presents as well-defined, yellow-brown plaques with atrophic centres and telangiectasia. The size of the lesions tends to be larger than those described in this case.
187
