Dermatology

Question 1

Isotretinoin

Answer 1

• Retinoid- oral- selective/ non-selective
• Cystic acne vulgaris, chemo agent
• Pregnancy Category X

Question 2

Tretinoin

Answer 2

• Retinoid- topical- decreases adhesiveness of epithelial cells, stimulation of mitotic activity/cell turnover
• Highly flammable

Question 3

Benzoyl peroxide

Answer 3

• Topical- Antibacterial action against acnes
• AE- redness, dryness, itching
• Avoid excess sunlight

Question 4

Sulfacetamide

Answer 4

• Topical- PABA antagonist, inhibits bacterial growth
• Acne vulgaris, acne rosacea, seb dermatitis
• CI for sulfur allergy

Question 5

Clobetasol propionate

Answer 5

• Topical steroid
• Eczema and psoriasis
• BLACK BOX- systemic absorption can cause reversible HPA axis suppression
• SE- cushing’s, hyperglycemia, skin thinning
• CI use in children under age 2

Question 6

Fluocinonide

Answer 6

• Topical steroid
• Eczema and psoriasis
• BLACK BOX- systemic absorption can cause reversible HPA axis suppression
• SE- cushing’s, hyperglycemia, skin thinning
• CI use in children under age 2

Question 7

Mometasone

Answer 7

• Topical steroid
• Eczema and psoriasis
• BLACK BOX- systemic absorption can cause reversible HPA axis suppression
• SE- cushing’s, hyperglycemia, skin thinning
• CI use in children under age 2

Question 8

Fluticasone

Answer 8

• Topical steroid
• Eczema and psoriasis
• BLACK BOX- systemic absorption can cause reversible HPA axis suppression
• SE- cushing’s, hyperglycemia, skin thinning
• CI use in children under age 2

Question 9

Triamcinolone

Answer 9

• Topical steroid
• Eczema and psoriasis
• BLACK BOX- systemic absorption can cause reversible HPA axis suppression
• SE- cushing’s, hyperglycemia, skin thinning
• CI use in children under age 2

Question 10

Hydrocortisone

Answer 10

• Topical steroid
• Eczema and psoriasis
• BLACK BOX- systemic absorption can cause reversible HPA axis suppression
• SE- cushing’s, hyperglycemia, skin thinning
• CI use in children under age 2

Question 11

Calcipotriol

Answer 11

• Synthetic Vit D3
• Plaque psoriasis, Topical- dermatitis
• CI hypercalcemia, Vit D toxicity
• DO NOT USE ON FACE

Question 12

Selenium sulfate

Answer 12

• Reduces corneocyte production
• OTC and Rx
• Dandruff, tinea versicolor

Question 13

Mupirocin

Answer 13

• Skin infection

Question 14

Triple antibiotic

Answer 14

• Bacitracin, neomycin, polymycin B

- Skin infection

Question 15

Nystatin

Answer 15

• Skin infection

Question 16

Imiquimod

Answer 16

• Warts, external genital warts, actinic keratosis, superficial BCC
• DO NOT USE with immunocompromise or kids with mulluscum

Question 17

Diclofenac gel

Answer 17

• NSAID, Topical pain relief

Question 18

Capsaicin

Answer 18

• Depletes supstance P, Topical pain relief

Question 19

Botulinum toxin

Answer 19

• Blocks ACh release
• OAB, chronic migrain, limb spasticity, hyperhidrosis, wrinkles
• AE- weakness, breathing difficuty
• BLACK BOX- distant spread of toxin effect (hours to weeks)

Question 20

Cyclosporine

Answer 20

• Occular emulsant, drops

- Chronically dry eyes, ocular inflammation, sjogren’s scleroderma

Question 21

Sulfacetamide

Answer 21

• Bacteriostatic

- Eye infection, conjuctivitis, superficial ocular infection

Question 22

Gentamicin

Answer 22

• Conjuctivitis, Keratitis, corneal ulcer, blepharitis, acute meibomianitis, dacrocystitis, amino glycoside
• OXOTOXICITY

Question 23

Erythromycin

Answer 23

• Superficial ocular infection of conjuctiva/cornea

Question 24

Latamoprost

Answer 24

• Prostaglandin analogue- receptor agonist- increases aqueous humor outflow
• open angle glaucoma, ocular HTN
• BLACK BOX- increased pigmentation of iris, eyelids, eyelashes

Question 25

Timolol

Answer 25

- Non-selective BB - Open angle claucoma, ocular HTN - CI/AE- same as BB - BLACK BOX- potential for systemic absorption

Question 26

Pilocarpine

Answer 26

- Cholinergic agonist, parasympathomimetic, causes miosis, decrease pressure in open angle glaucoma or ocular HTN - Sjogren's/ dry mouth, Acute closed angle

Question 27

Atropine

Answer 27

- Anti-cholinergic- Paralysis of ciliary muscle (cycloplegia) - Treatment of functional ambiyopia, heart block, bradycardia, hyperhidrosis - AE- increase in BP

Question 28

Nepafenac

Answer 28

- NSAID - Pain, inflammation associated with cataract surgery - AE- increased bleeding, delayed healing, corneal effects, DON'T WEAR CONTACTS

Question 29

Neomycin + Polymyxin B + Hydrocortisone

Answer 29

- Antibacterials and steroid - Otitis externa, mastoidectomy infxns - OTOTOXICITY- BLACK BOX- can cause permanent sensorineural hearing loss- Cochlea, organ of corti

Question 30

Olopatadine

Answer 30

- Anti-histamine, Mast cell stabilizer, eye drops - occular itching, allgergic conjuctivitis - AE- cold like symptoms, pharyngitis

Question 31

Cromolyn sodium

Answer 31

- Anti-histamine, Mast cell stabilizer, oral inhaler - Eye, nose - AE- N/V/D, urticaria - BLACK BOX- decrease does with Kd or Lv dysfunction

Question 32

Oxymetazoline

Answer 32

- Afrin/visine - Shrink nasal membranes and nasal.ocular vessels - Limit to 3 day use- may cause rebound congestion

Question 33

Phenylephrine

Answer 33

- Sudafed pill/spray - Shrink nasal membranes and nasal.ocular vessels - Limit to 3 day use- may cause rebound congestion

Question 34

Beciomethasone

Answer 34

- Inhaled steroids- corticosteroids | - Allergies

Question 35

Budesonide

Answer 35

- Inhaled steroids- corticosteroids | - Allergies

Question 36

Fluticasone

Answer 36

- Inhaled steroids- corticosteroids | - Allergies, also formulated for eczema/topical

Question 37

mometasone

Answer 37

- Inhaled steroids- corticosteroids | - Allergies, also formulated for eczema/topical