Developmental Biology Flashcards

(54 cards)

1
Q

a cell that has the potential to develop into any cell type is called

A

Totipotent cell

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2
Q

a cell becomes committed to a particular cell fate

A

determination

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3
Q

many kind of plants can be cloned from

A

isolated single cells

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4
Q

what serves as the model for the genetic control of development

A

Drosophila

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5
Q

what is responsible for the determination of dorsal-ventral axis, anterior-posterior axis

A

Egg polarity genes

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6
Q

how many stages does the Drosophila go through before developing into an adult fly

A

3 larval stages and a pupa

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7
Q

what stage does the Drosophila undergo metamorphosis

A

at the pupa

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8
Q

what are the stages in the early development in Drospholia Embryo

A

a. single-celled diploid zygote
b. multinucleate syncytium
c. syncytial blastoderm
d. cellular blastoderm

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9
Q

what is established at the 2-hour embryo mark

A

anterior-posterior and dorsal-ventral axes

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10
Q

what is established at the 10 hours embryo mark

A

number and orientation of the body segments

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11
Q

when is the identity of each individual segment

A

the adult stage

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12
Q

what gene is responsible for determination of number and polarity of body segments

A

Segmentation genes

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13
Q

what gene is responsible for establishment of identity of each segments

A

homeotic genes

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14
Q

determination of anterior-posterior and dorsal-ventral axes of the embryo. is called

A

material origin

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15
Q

what is the protein in which its concentration gradient affects the developmental fate of the surrounding region

A

morphogen

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16
Q

what gene SPECIFICALLY determines the dorsal-ventral axis

A

dorsal gene

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17
Q

what genes SPECIFICALLY determines the anterior-posterior axis

A

bicoid gene, nanos gene, hunchback gene

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18
Q

what gene is responsible for anterior structures gene EXPRESSION, stimulates hunchback

A

bicoid in ovary

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19
Q

what gene is responsible for posterior structures, inhibits translation of hunchback mRNA

A

nanos in ovary

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20
Q

what gene regulates TRANSCRIPTION of genes responsible for anterior structures

A

hunchback

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21
Q

what gene takes part in the development of mesodermal tissues

A

twist, expressed in embryo

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22
Q

types of segmentation genes

A

homeotic genes in Drosophila
Homeobox genes in other organisms
Epigenetic changes in development

23
Q

what controls the differentiation of the embryo into individual segments

A

segmentation genes

24
Q

What broad region gap differentiation?

25
what affects alternate segments?
pair-rule genes
26
what affects your development of individual segments?
segment-polarity gene
27
what is the effect of gap gene mutation
delete group of adjacent segment
28
what is the effect of pair-rule mutation
delete same part of pattern in every other segment
29
what is the effect of segment-polaroity gene
affect polarity of segmnet, replacement
30
example of gap gene
hunchback, kruppel, knirps, giant, tailles
31
exmaple of pair-rule gene
runt, hairy, fushi tarazu, odd-paired, sloppy paired
32
example of segment-polarity genes
engrailed, wingless, gooseberry,cunitus interruputs
33
homeotic gene in Drosophilia affects
identity of segments
34
homeobox genes in other organisms affects
genes encoding DNA-binding proteins, these protein usually play a regulatory rule
35
which gene encodes transcription factors that help determine the identity of body regions
Hox genes
36
what homeotic mutation substitutes legs for the antenna of a fruit fly
Anternnapedia
37
what complexes are homeotic gene present in
2 complexes, antennapedia complex & bithorax complex
38
Hox genes in drosophilia are similar to
mammals
39
do genes control the development of flowers in plants YES/ FALSE
YES
40
what did the flower produced by Arabidopsis thaliana produce
Four sepals, four white petals, six stamens, two carpels
41
injured cells dying in an uncontrolled manner is called
necrosis
42
is apoptosis and necrosis the same process
nope, they are distinct process
43
describe apoptosis
1. DNA is degraded 2. Cytoplasm and nucleus shrink, nucleus fragments 3. Vesicles and the cell are engulfed by macrophage 4. macrophages phagocytizes apoptotic cell.
44
describe necrosis
1. cell swells 2. cell lyses and releases cytoplasmic material
45
expression of eyeless gene causes
development of an eye on the leg of a fruit fly
46
what molecules elicit an immune reaction
antigen
47
what protein that binds an antigen and marks it for destruction by phagocytic cells
antibody
48
the production of antibodies by B cells is what type of immunity
humoral immunity
49
what immunity depends on T cells
Cellular immunity
50
what immunity gives primary response, memory cells, secondary response
clonal selection
51
B cells and T cells found in
bone marrow, thymus
52
descrube structure of immunoglobin molecule
four polypeptide (2 light chains and 2 heavy chains) combine to form a Y-shaped structure
53
antibody diversity is produced by
somatic recombination
54
why does a Tcell receptor have 2 polypeptide chains
because one tranverse the cell membrane and the other projects away form the cell and binds antigens