diarrhoea Flashcards

(32 cards)

1
Q

symptoms associated

A
  • crampy abdominal pain
  • fever
  • blood stained stool
  • steatorrhoea
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2
Q

what are common causes of secretory diarrhoea

A
  • enterotoxins (cholera, e.coli, c.diff)
  • hormones
  • bile salts
  • fatty acids
  • laxatives
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3
Q

why does diarrhoea occur

A

because of damage to the intestinal mucosal cell so that there is a loss of fluid and blood

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4
Q

common causes

A
  • shigella
  • UC
  • crohns
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5
Q

what diseases do not cause ‘true’ diarrhoea

A
  • IBS
  • colorectal cancer
  • diverticular disease
  • faecal impaction
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6
Q

does acute diarrhoea require investigation

A

no

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7
Q

how long does travellers diarrhoea last

A

2-5 days

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8
Q

symptoms of acute diarrhoea

A
  • fever
  • abdominal pain
  • vomiting
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9
Q

what can occur if diarrhoea is severe

A

dehydration

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10
Q

who is at risk of dehydration

A

very young and elderly

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11
Q

what is treatment for acute

A

fluid and electrolyte replacement

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12
Q

what is given to infants with acute diarrhoea

A

rehydration solutions e.g. sodium chloride

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13
Q

what do anti-diarrhoeals impair the clearance of

A

any pathogen from bowel

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14
Q

when are antibiotics occasionally necessary

A
  • infective gastroenteritis
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15
Q

does chronic diarrhoea need investigation

A

yes

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16
Q

what is first line investigation for chronic diarrhoea if stool culture negative

A

colonoscopy with ileoscopy

17
Q

first line investigation for chronic diarrhoea with blood

A

colonoscopy with biopsies

18
Q

what causes colonic lesions on colonoscopy

A
  • UC
  • crohns
  • carcinoma
19
Q

what is done for malabsorption

A
  • blood test

- jejunal biopsy

20
Q

what disease cause small bowel lesions

A
  • coeliac
  • tropical sprue
  • giardia
21
Q

what diseases cause pancreatic lesions

A
  • chronic pancreatitis

- carcinoma

22
Q

what investigations are done for water/loose stools

A
  • flexible sigmoidoscopy
  • colonoscopy
  • biopsy
23
Q

what diseases cause colonic lesions

A
  • IBD

- pseudomembraneous colitis

24
Q

when can pseudomembraneous colitis occur

A

following the use of antibiotics

25
what is the causative agent of pseudomembraneous colitis
C.diff
26
what is an under-diagnosed cause of chronic diarrhoea
bile acid malabsorption
27
when does bile acid diarrhoea occur
when the terminal ileum fails to reabsorb bile acids
28
what does an increase in bile acid in the colon cause
diarrhoea
29
how is bile acid malabsorption diagnosed
SeHCAT test
30
treatment of bile acid malabsorption
bile salt sequestrants e.g. colestyramine
31
what do bile salt sequestrants do
they bind and inactivate the action of bile acids in the colon
32
is chronic diarrhoea a symptom of HIV
yes