Diltiazem G5

Question 1

Diltiazem Class

Answer 1

• Calcium channel blocker
• Antidysrhythmic

Question 2

Diltiazem MOA

Answer 2

• Slows extracellular calcium ion influx across myocardial cell membranes
• Slows conduction through the SA node and the AV node
• Slows ventricular conduction rates in atrial fibrillation and atrial flutter

Question 3

Diltiazem Indications

Answer 3

• Atrial fibrillation with rapid ventricular rate
• Atrial flutter with rapid ventricular rate
• Supraventricular tachycardia second-line to administration of adenosine

Question 4

Diltiazem Adult dose

Answer 4

• 0.25 mg/kg (usually 20 mg) over 2 minutes
• May repeat the dosage 0.35 mg/kg (usually 25 mg) in 15 minutes
• Infusion: 5.0 to 15 mg/hour

Question 5

Diltiazem Contraindications

Answer 5

• Known hypersensitivity to the drug
• Hypotension
• Myocardial infarction
• Cardiogenic shock
• Ventricular tachycardia
• Second-degree and third-degree heart block
• Wolff-Parkinson-White (WPW) syndrome
• Not recommended for use with pediatric patients

Question 6

Diltiazem Adverse effects

Answer 6

• Hypotension
• Dysrhythmias
• Bradycardia

Question 7

Diltiazem Pediatric dose

Answer 7

Not recommended with kids